广东省成人血脂异常患病率及其危险因素的相关性研究

doi:10.13217/j.scjpm.2013.02.011

华南预防医学 ›› 2013, Vol. 39 ›› Issue (2): 11-17.doi: 10.13217/j.scjpm.2013.02.011

广东省成人血脂异常患病率及其危险因素的相关性研究

莫景富¹, 宋秀玲², 许燕君², 许晓君², 何群², 蔡秋茂², 徐浩锋², 夏亮²

1.汕头大学医学院公共卫生硕士教育中心,广东汕头515041;2.广东省疾病预防控制中心

收稿日期:2012-12-11 出版日期:2013-04-20 发布日期:2013-09-23
通讯作者: 宋秀玲 E-mail:songxl918@163.com
作者简介:莫景富(1984—),男,在读硕士研究生,主要从事慢性病与卫生统计学研究
基金资助:

Association study of prevalence of dyslipidemia and its risk factors among adults in Guangdong Province

MO Jing-fu, SONG Xiu-ling, XU Yan-jun, XU Xiao-jun, HE Qun, CAI Qiu-mao, XU Hao-feng, XIA Liang

MPH Education Center, Shantou University Medical College, Shantou 515041, China

Received:2012-12-11 Online:2013-04-20 Published:2013-09-23
Contact: E-mail:songxl918@163.com
About author:
Supported by:

摘要/Abstract

摘要： 目的了解广东省18岁及以上人群血脂异常患病率及其危险因素，为制定相应干预策略提供科学依据。方法采用多阶段分层随机整群抽样方法于2010年抽取广东省6个监测县（区、市）18岁及以上居民进行问卷调查（人口统计学资料、吸烟、喝酒、饮食和体力活动等）、体格检查（体重、身高和血压的测量）及血生化检测（甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、总胆固醇和血糖的检测），采用单因素、多因素非条件logistic回归分析血脂异常的危险因素。结果共调查3577人，其中男性1615人，平均年龄（50.28±14.05）岁，女性1962人，平均年龄（49.21±13.51）岁。广东省18岁及以上人群血脂异常总患病率为60.7%（2173/3577），标化率为56.0%。男女性患病率分别为68.9%（1113/1615）和54.0%（1060/1962），男性高于女性（P<0.01）。城市和农村居民患病率分别为61.0%（1088/1785）和60.5%（1085/1792），城乡差异无统计学意义（P>0.05）。其中高胆固醇血症患病率为2.5%（标化率4.1%），混合型高脂血症患病率为1.9%（标化率3.3%），高甘油三酯血症患病率为4.5%（标化率5.0%），低高密度脂蛋白胆固醇血症患病率为57.3%（标化率49.9%）。多因素非条件logistic回归分析结果表明，超重（OR=1.554）、肥胖（OR =2.321）、腹部肥胖（OR =1.300）、吸烟（轻度、中度和重度吸烟OR值分别为2.189、2.042和1.874）和蔬菜摄入量<300g/d（OR =1.389）是影响广东省18岁及以上人群血脂异常的危险因素，体质偏轻（OR =0.539）、身体活动活跃（OR =0.601）和身体活动充分（OR =O.658）是广东省18岁及以上人群血脂异常的保护因素。结论广东省18岁及以上人群血脂异常患病率已经达到较高水平，血脂异常以低高密度脂蛋白胆固醇血症和高甘油三酯血症为主，建议加强血脂异常的综合防治力度。

Abstract: Objective To explore the prevalence and related risk factors of dyslipidemia among adults in Guangdong Province, and to provide evidence for prevention and intervention of dyslipidemia. Methods In habitants aged 18 years and over were chosen by using multi-stage stratified cluster sampling method from 6 counties in Guangdong Province in 2010. Questionnaire survey (demographics, smoking, drinking, diet, physical activity, etc.), medical examination (measurement of weight, height, and blood pressure), and biochemical detection [triglycerides, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), total cholesterol (TC) and blood sugar] were conducted among the residents. Models of the univariate and multivariate non-conditional logistic regressions were used to analyze the risk factors of dyslipidemia. Results A total of 3577 people were surveyed. Of them, 1615 were males (average age 50.28±14.05 years) and 1962 females (average age 49.21±13.51 years). The overall prevalence of dyslipidemia was 60.7% (2173/3577), the standardized prevalence rate was 56.0%. The prevalence rates in men (68.9%, 1113/1615) was higher than that in women (54.0%, 1060/1962) (P<0.01). The prevalences in urban and rural populations were 61.0% (1088/1785) and 60.5% (1085/1792) (P>0.05). The prevalences of isolated hypercholesterolemia, mixed hyperlipidemia (elevated TC and triglycerides), isolated hypertriglyceridemia and isolated low HDL-C were 2.5% (standardized prevalence rate 4.1%), 1.9% (standardized prevalence rate 3.3%), 4.5% (standardized prevalence rate 5.0%) and 57.3% (standardized prevalence rate 49.9%), respectively. Multivariate logistic regression analysis showed that overweight (OR=1.554), obesity (OR=2.321), centra lobesity (OR=1.300), smoking [the mild smoking group (OR=2.189), moderate smoking group (OR=2.042), heavy smoking group (OR=1.874)] and vegetables intake < 300 grams/day (OR=1.389) were the risk factors, and the lighter weight groups (OR=0.539), vigorous physical activity (OR=0.601) and moderate physical activity (OR=0.658) were the protective factors for dyslipidemia in Guangdong. Conclusion The prevalence of dyslipidemia has been in a high level among residents aged 18 years old and over in Guangdong Province and the hypertriglyceridemia and low HDL-C were the most predominant. Strengthening measures should be taken to prevent the people from getting dyslipidemia.

中图分类号:

莫景富, 宋秀玲, 许燕君, 许晓君, 何群, 蔡秋茂, 徐浩锋, 夏亮. 广东省成人血脂异常患病率及其危险因素的相关性研究[J]. 华南预防医学, 2013, 39(2): 11-17.

MO Jing-fu, SONG Xiu-ling, XU Yan-jun, XU Xiao-jun, HE Qun, CAI Qiu-mao, XU Hao-feng, XIA Liang. Association study of prevalence of dyslipidemia and its risk factors among adults in Guangdong Province[J]. S China J Prev Med, 2013, 39(2): 11-17.

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广东省成人血脂异常患病率及其危险因素的相关性研究

Association study of prevalence of dyslipidemia and its risk factors among adults in Guangdong Province

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