华南预防医学 ›› 2018, Vol. 44 ›› Issue (3): 227-230.doi: 10.13217/j.scjpm.2018.0227

• 论著 • 上一篇    下一篇

深圳居民膳食中晚期糖基化终末产物暴露水平调查

朱凤1,李维克1,何建安2,3,肖文竹2,刘春晓2,3   

  1. 1.深圳市南山区疾病预防控制中心,广东 深圳518054;2.深圳出入境检验检疫局保健中心;3.深圳市检验检疫科学研究院
  • 收稿日期:2017-11-17 修回日期:2017-11-17 出版日期:2018-07-03 发布日期:2018-07-20
  • 作者简介:朱凤(1978—),女,硕士研究生,副主任医师,研究方向:营养与食品安全
  • 基金资助:
    深圳市科技创新委员会科技计划项目(JCYJ20150402152407821)

Levels of dietary exposure to advanced glycation end products in residents of Shenzhen

ZHU Feng1,LI Wei-ke1, HE Jian-an2,3,XIAO Wen-zhu2,3,LIU Chun-xiao2,3   

  1. 1. Nanshan District Center for Disease Control and Prevention of Shenzhen City, Shenzhen 518054,China; 2.International Travel Health Care Center, Exit-entry Inspection and Quarantine Bureau; 3.Shenzhen Academy of Inspection and Quarantine
  • Received:2017-11-17 Revised:2017-11-17 Online:2018-07-03 Published:2018-07-20

摘要: 目的了解深圳主要市售食品中晚期糖基化终末产物(advanced glycation end products,AGEs)的含量,评估深圳市居民AGEs膳食暴露的水平。方法采用竞争酶联免疫法检测11类食品中的AGEs含量,结合2011年深圳居民食物消费量调查数据,采用点评估方法,计算深圳居民AGEs膳食暴露量,计算不同食物对AGEs摄入的贡献率。结果共检测11类食品196份,检出AGEs平均含量为44.28mg/kg,最高可达821.74mg/kg。调味品(不包括食盐)中AGEs含量最高,平均为628.60mg/kg。肉类及其制品、糖果蜜饯、乳类及其制品和谷类及其制品中AGEs含量高于水果蔬菜、饮料、薯类及其制品。深圳市居民的AGEs膳食平均暴露水平为31.85mg/d?人,偏高暴露量(P97.5)为53.16mg/d?人。调味品(不包括食盐)、谷类及其制品和肉类及其制品对AGEs膳食摄入的贡献率较高。2~5岁女童AGEs膳食暴露贡献率前3位分别是乳及乳制品(26.06%)、调味品(24.78%)、谷类及其制品(18.55%),其他各组人群AGEs膳食暴露贡献率前3位的食品均是调味品、谷类及其制品和肉类及其制品。结论深圳居民每天通过食品摄入一定量的AGEs,建立食品中AGEs含量的数据库,完善相关人群食源性AGEs摄入方面的指导是可行的。

Abstract: ObjectiveTo investigate advanced glycation end products (AGEs) content in food and assess the dietary exposure to AGEs among Shenzhen residents.MethodsAGEs contents in 11 kinds of foods were tested by competitive enzyme-linked immunosorbent assay. Based on the food consumption survey data of Shenzhen residents in 2011, the point assessment model was used to estimate dietary exposure to AGEs in the residents and calculate the contribution of different foods to AGEs intake.ResultsAGEs was found in the 11 kinds of foods, with an average content of 44.28 mg/kg and a maximum content of 821.74 mg/kg. The highest AGEs content was found in seasoning (excluding salt), with an average content of 628.60 mg/kg. AGEs contents in meat and its products, candy confection, milk and its products, grain and its products were higher than those in fruits and vegetables, beverage, potato and its products. The mean dietary intake of AGEs was 31.85 mg/dP for the residents. The dietary intake of AGEs for high-consuming populations(P97.5) was 53.16 mg/dP. The major food contributors to AGEs were seasoning (excluding salt), grain and its products, meat and its products for the residents. Milk and its products (26.06%), seasoning(24.78%) and grain and its products(18.55%) were the first three of AGEs exposure for girls aged 2-5 years, while seasoning, grain and its products, and meat and its products were the first three of AGEs exposure for other groups.ConclusionDaily dietary AGEs intake was found among the surveyed residents in Shenzhen. It is feasible to establish dietary AGEs database and improve the guidance on the dietary AGEs intake of related groups.

中图分类号: 

  • R151.3