川东北地区3 146例新发肺癌病例特征分析

doi:10.12183/j.scjpm.2021.1397

摘要/Abstract

摘要： 目的分析川东北地区2016—2020年新发肺癌病例特征,为本地区肺癌防治工作提供科学依据。方法川东北地区3 146例新发肺癌病例资料来源于2016—2020年南充市2家病历管理信息系统,采用描述流行病学分析方法对新发肺癌病例特征进行分析。结果新发肺癌病例3 146例中,2016、2017、2018、2019、2020年分别为570、604、591、658、723例,病例数逐年增多。男性病例占53.3%,以60~76岁为主（47.5%）。2016—2020年每年新发肺癌病例性别、病理组织学分类分布差异均无统计学意义（均P>0.05）,年龄分布差异有统计学意义（P<0.01）,发病呈年轻化趋势。临床表现均主要有咳嗽（75.08%）、咳血或咯血（31.98%）、胸痛（64.02%）、气短或喘鸣（50.25%）、发热（39.00%）、吞咽困难（20.79%）。病理组织学分类以腺癌为主（1 515例,占48.16%）,其次是鳞癌（824例,占26.19%）和小细胞癌（560例,占17.80%）,其他分类247例,占7.85%。2016—2020年不同性别的肺癌患者病理组织学分类差异有统计学意义（均P<0.01）,男性中病理组织学分类主要为鳞癌,女性中病理组织学分型主要为腺癌。2016、2017、2018年不同年龄的肺癌病例病理组织学分类分布差异均有统计学意义（P<0.01或P<0.05）。结论川东北地区2016—2020年新发肺癌发病呈年轻化趋势,以腺癌、鳞癌多见,应根据肺癌病例特征采取有效干预措施,减轻疾病负担。

关键词: 肺癌, 病例特征, 流行特征, 病理分型

Abstract: Objective To analyze the characteristics of new cases of lung cancer in the northeast negion of Sichuan from 2016 to 2020, so as to provide scientific basis for the prevention and treatment of lung cancer in this region. Methods The data of 3 146 new cases of lung cancer in the northeast negion of Sichuan were derived from two medical record management information systems in Nanchong from 2016 to 2020. The new cases of lung cancer were analyzed by descriptive epidemiological analysis method. Results Among the 3 146 new cases of lung cancer, there were 570, 604, 591, 658 and 723 cases in 2016, 2017, 2018, 2019 and 2020 respectively, and the number of cases increased year by year. Male cases accounted for 53.3%, mainly aged 60-76 years （47.5%）. There was no significant difference in gender and histopathological classification distribution of new lung cancer cases from 2016 to 2020 （all P>0.05）, but there was significant difference in age distribution （P<0.01）, and the incidence showed a younger trend. The main clinical manifestations were cough （75.08%）, hemoptysis or spit blood （31.98%）, chest pain （64.02%）, shortness of breath or wheezing （50.25%）, fever （39.00%） and dysphagia （20.79%）. Adenocarcinoma was the main histopathological classification （1 515 cases, accounting for 48.16%）, followed by squamous cell carcinoma （824 cases, accounting for 26.19%） and small cell carcinoma （560 cases, accounting for 17.80%）, and 247 other types, accounting for 7.85%. There was significant difference in histopathological classification of lung cancer patients between different genders from 2016 to 2020 （all P<0.01）. The histopathological classification of males was mainly squamous cell carcinoma and that of females was mainly adenocarcinoma. There were statistically significant differences in the distribution of histopathological classification of lung cancer cases of different ages in 2016, 2017 and 2018 （P<0.01 or P<0.05）. Conclusion The incidence of lung cancer in the northeast negion of Sichuan from 2016 to 2020 tends to be younger, with adenocarcinoma and squamous cell carcinoma more common, effective interventions should be taken according to the characteristics of lung cancer cases to reduce the disease burden.

Key words: Lung cancer, Case characteristics, Epidemiological characteristics, Pathological classification

中图分类号:

R195.4

敬世霞, 苏明萍, 袁映红. 川东北地区3 146例新发肺癌病例特征分析[J]. 华南预防医学, 2021, 47(11): 1397-1400.

JING Shi-xia, SU Ming-ping, YUAN Ying-hong. Characteristics of 3,146 new cases of lung cancer in the northeast region of Sichuan[J]. South China Journal of Preventive Medicine, 2021, 47(11): 1397-1400.

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