关键词: 耐多药结核病, 治疗, 影响因素, 结核杆菌

Abstract: Objective To explore the status of untreated patients with multidrug-resistant tuberculosis （MDR-TB） in Guangdong Province and its influencing factors. Methods The MDR-TB patients diagnosed in 10 designated medical institutions in 9 prefecture-level cities in Guangdong Province from 2018 to 2019 were selected, and they were divided into the treatment group and the non-treatment group according to whether they received treatment. The questionnaire was used to collect individual and area-related factors. The two-level Logistic regression model was used to explore the influencing factors of whether MDR-TB patients received treatment. Results Among 530 MDR-TB patients, 398 cases （75.1%） were included in the treatment group, and 132 cases （24.91%） were in the non-treatment group, with a male to female ratio of 2.4∶1. The two-level Logistic regression model showed that MDR-TB patients with junior high school, senior high school and above education （OR=4.302, 15.858）, agricultural workers, retired or other workers （OR=5.246, 16.662, 5.244） were more likely to receive treatment. MDR-TB patients with registered residence in other provinces （OR=0.365） were not easy to receive treatment. Conclusion The education, occupation, and registered residence location are the influencing factors of untreated patients with MDR-TB in Guangdong Province, which indicated feasible prevention and control measures should be taken for these high-risk groups to improve the inclusion rate of MDR-TB patients in Guangdong Province.

Key words: Multidrug-resistant tuberculosis, Treatment, Influencing factor, Mycobacterium tuberculosis