华南预防医学 ›› 2024, Vol. 50 ›› Issue (12): 1120-1123.doi: 10.12183/j.scjpm.2024.1120

• 论著 • 上一篇    下一篇

2018—2022年晋江市HIV感染者/艾滋病患者生存时间及其影响因素分析

林巧莉1, 许名源2, 许毓颖1   

  1. 1.晋江市医院(上海市第六人民医院福建医院),福建 晋江 362200;
    2.晋江市疾病预防控制中心
  • 收稿日期:2024-01-25 出版日期:2024-12-20 发布日期:2025-01-06
  • 通讯作者: 许毓颖,E-mail:348475155@qq.com
  • 作者简介:林巧莉(1991—),女,大学本科,主管护师,从事流行病学研究工作

Analysis of the survival time and its influencing factors among HIV-infected/AIDS patients in Jinjiang City, 2018-2022

LIN Qiaoli1, XU Mingyuan2, XU Yuying1   

  1. 1. Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian Campus, Jinjiang, Fujian 362200, China;
    2. Jinjiang Center for Disease Control and Prevention
  • Received:2024-01-25 Online:2024-12-20 Published:2025-01-06

摘要: 目的 了解2018—2022年晋江市HIV感染者/艾滋病患者生存时间及其影响因素。方法 通过中国疾病预防控制信息系统艾滋病综合防治信息系统收集2018—2022年晋江市HIV感染者/艾滋病患者的病例资料,使用单、多因素Cox比例风险回归模型分析HIV感染者/艾滋病患者生存时间的影响因素。结果 2018—2022年登记现住址为晋江市的HIV感染者/艾滋病患者共937例,男性774例,女性163例。截至观察终点,937例报告病例中,艾滋病相关死亡151例,艾滋病相关病死率为16.12%,平均生存时间为154.55个月(95% CI:138.20~170.90)。多因素Cox比例风险模型结果显示,基线CD4+T淋巴细胞200~<350个/μL(HR=0.21,95% CI:0.10~0.43)、≥350个/μL(HR=0.18,95% CI:0.09~0.37)、接受ART(HR=0.07,95% CI:0.04~0.13)死亡风险较低。结论 基线CD4+T淋巴细胞水平以及ART是HIV感染者/艾滋病患者生存的影响因素。

关键词: HIV感染者/艾滋病患者, 抗病毒治疗, 生存时间, 影响因素

Abstract: Objective To analyze the survival time of HIV-infected/AIDS patients and its influencing factors in Jinjiang City from 2018 to 2022. Methods The case data of HIV-infected/AIDS patients in Jinjiang City from 2018 to 2022 were derived from the “AIDS Comprehensive Prevention and Control Data Information Management System” of China Disease Prevention and Control Information System, and the influencing factors of the survival time of HIV-infected/AIDS patients were analyzed using univariate and multivariate Cox proportional risk regression models. Results From 2018 to 2022, a total of 937 HIV-infected/AIDS patients with current addresses in Jinjiang City were registered, including 774 males and 163 females. At the end of observation, 151 of the 937 reported cases were AIDS-related deaths, the AIDS-related fatality rate was 16.12%, and the mean survival time was 154.55 months (95% CI: 138.20-170.90). Multivariate Cox proportional risk model results showed that baseline CD4+T lymphocytes were 200 - < 350/μL (HR=0.21, 95% CI: 0.10-0.43), ≥350 /μL (HR=0.18, 95% CI: 0.09 - 0.37), and antiviral therapy (ART) (HR=0.07, 95% CI: 0.04 - 0.13) had a lower risk of death. Conclusion Baseline CD4+T lymphocyte levels and ART are factors influencing survival in HIV-infected/AIDS patients.

Key words: HIV-infected/AIDS patients, Antiviral therapy, Survival time, Influencing factor

中图分类号: 

  • R183.9