Abstract: Objective To analyze the epidemiological characteristics and spatiotemporal distribution patterns of acute hemorrhagic conjunctivitis in Bao' an District, Shenzhen, from 2013 to 2023, and to provide a scientific basis for developing prevention and control strategies. Methods Surveillance data on acute hemorrhagic conjunctivitis cases in Bao' an District (2013—2023) were collected. Epidemiological characteristics were analyzed using descriptive statistics. spatiotemporal scan analysis was conducted using SaTScan V9.5. Results A total of 8 384 acute hemorrhagic conjunctivitis cases were reported in Bao' an District, Shenzhen, from 2013 to 2023. The annual incidence rate ranged from 2.29 to 36.67 per 100 000, with an average annual incidence rate of 14.65 per 100 000. Males had a significantly higher incidence than females (P<0.01). The highest incidence rate was found in the age group of 1 to 10 years. The peak incidence occurred in the months of September and October. The high-risk populations included workers, homemakers/ unemployed individuals, and students. Subdistricts with elevated incidence rates were Fuyong, Shiyan, Fuhai, and Songgang. The spatiotemporal scan analysis identified seven statistically significant clusters, covering eight streets. with spatial shifts observed over time: clusters initially concentrated in Fuyong, Shiyan, and Songgang subdistricts gradually transitioned to Xin' an and Xixiang subdistricts. Conclusions From 2013 to 2023, the incidence of acute hemorrhagic conjunctivitis in Bao' an District, Shenzhen, exhibited a rising-then-falling trend, with distinct regional and demographic distribution characteristics. Significant spatiotemporal clustering was identified, highlighting the need for comprehensive prevention and control measures targeting high-risk areas and populations.

Key words: Acute hemorrhagic conjunctivitis, Epidemic characteristics, Spatiotemporal clustering, Spatiotemporal scanning analysis