Abstract: Objective To investigate intake levels of trans fatty acid (TFA)-containing food. Methods Districts of Yuexiu, Liwan, Huangpu, Baiyun, Panyu, Huadu, and Nansha in Guangzhou were chosen by multi stage random sampling method and considering differences in the level of regional development. Six resident committees were systematically sampled in each district. Forty households were randomly chosen in each committee. All family members aged 3 years and over were investigated. The self designed questionnaire covered the basic situation of households, basic personal situation and the consumption frequency of TFA-containing food in the past three months. The basic situation of households included family income, number of household members, ethnic, etc.The basic personal situation included age, gender, occupation, and so on. The data were analyzed using a descriptive epidemiologic method. Results A total of 5 244 residents aged 3 years and over were investigated, of whom 2 565 were male and 2 679 were female, and the ratio of male to female was 1∶0.96. The number (percentage) in the groups aged 3 to 6, 7 to 12, 13 to 17, 18 to 49, and≥50 years were 931 (17.8%), 1 064 (20.3%), 1 063 (20.3%), 1 797 (34.2%), and 389 (7.4%), respectively. Their education level was mainly middle school or higher , accounting for 60.1%（3 152/5 244) of the total population. Percentages of average monthly household income in 2011 at ＜3 000, 3 000－, 5 000－ and ≥8 000 Yuan were 22.5% (1 178/5 244), 22.0% (1 148/5 244), 19.9% (1 043/5 244), and 32.5% (1 704/5 244), respectively. Foods containing much more TFA-were milk, hydrogenated vegetable oil, bread, pastries, frozen drinks, fresh meat and products, and fried food, and the consumed contents were 141.18, 25.55, 25.34, 19.43, 19.33, 19.09, and 17.18 g/d, respectively. The average intake levels of milk, bread, pastries, puffed food, fried food, quick frozen food, frozen drinks, solid beverage, and chocolate candies between different aged groups were significantly different (all P＜0.05 or P<0.01), of which average intake levels in groups aged 7－12 and 13－17 years were higher than other age groups. Average intake levels of milk, bread, pastries, fried food, quick frozen food, frozen drinks, solid beverage, chocolate, and candies between different family income groups were significantly different (all P＜0.05 or P<0.01), of which the average intake levels in ≥8 000 Yuan group were higher than other groups. Conclusion School age children and adolescents aged 7 to 17 years in Guangzhou had higher intake levels of TFA-containing food. It is necessary to carry out further research in this population, to lay a foundation for the following risk assessment.