Abstract: Objective To study the relationship between household biomass fuels use and lower respiratory tract symptoms in rural area of Guangzhou City.Methods A systematic sampling survey was performed in residents aged over 6 years in rural area in Zengcheng District of Guangzhou, to obtain the information of indoor biomass fuels use and human lower respiratory tract symptoms. A multiple factor logistic analysis was carried out to test the relationship. Status factors of age, gender, smoke, indoor ventilation and kitchens ventilating devices were controlled in the analysis.Results A total of 266 households were investigated and 645 subjects were included in the study. Among the subjects, 478（74.1%）used biomass fuels and 167（25.9%）used clean energy. The prevalence of lower respiratory tract symptoms (containing any one of the symptoms of dry cough, expectoration, asthma, chest tightness or dyspnea) in past half year in biomass fuels group and clean energy group were 51.5%（246/478） and 41.3%（69/167）, respectively. In the multiple logistic regression model, the risks of expectoration（OR=1.90, 95% CI: 1.23-2.93）, asthma (OR=6.71, 95% CI: 1.74-25.85), chest congestion (OR=2.41, 95% CI: 1.02-5.72) and dyspnea (OR=5.99, 95% CI: 1.23-29.28) in biomass fuels group were all higher than those in clean energy group.The risk of lower respiratory tract symptoms was significantly associated with the frequency of biomass fuels use for symptoms experienced (OR=1.72, 95% CI: 1.14-2.59) and often appearing symptoms (OR=4.10, 95% CI: 1.40-12.04) in the group of using biomass fuels every day.Conclusion Indoor biomass fuels use may be an important risk factor for respiratory tract symptoms in rural area in Guangzhou. 【Key words】 Biofuel; Indoor air pollution; Respiratory tract disease