Abstract: ObjectiveTo understand the prevalence of cigarette smoking among employed floating population aged 18-59 years in Guangdong Province so as to provide evidence for developing prevention and control measures．MethodsUsing special survey data of China chronic disease and risk factor surveillance for migrant population (2012), 12 survey points were selected by stage stratified equal-sized cluster sampling method based on six occupational groups．Demographic information including gender, age, education level, and occupation, and cigarette smoking status and factors influencing smoking behavior of the employed floating population were collected by face-to-face interviews．Logistic regression analysis was used to determine the factors influencing smoking behavior. ResultsA total of 4 116 valid subjects were collected, including 2 271 males and 1 845 females. The prevalence rates of current smoking and daily cigarette smoking were 27.73% and 24.85%, respectively. The risk of smoking for men was 81.294 times that for women. The possibility of smoking in group aged 50 to 59 years was 1.639 times that in group aged 18 to 29 years; the probability of smoking for divorcees was 13.128 times that for unmarried persons; the probabilities of smoking for those who drank 30 days before and within 30 days were 2.858 and 1.410 times that for those who never drank within a year, respectively；the probabilities of smoking for those who were occasionally, sometimes, and often difficult to fall asleep were 2.135, 1.827, and 2.133 times that for those who were never difficult to fall asleep. The probability of smoking for those whose levels of education were junior and senior high schools, college and above was lower than that for those whose levels of education were primary school and below (OR=0.427, 0.491). ConclusionMale smokers were more than female ones among the employed floating population aged 18~59 years in Guangdong Province. Females and higher levels of education were protective factors for smoking, but age, divorce or separation, drinking habits, and sleep disorder were risk factors.