Abstract: Objective To analyze the status and influencing factors of different frequency hearing loss among noise-exposed workers in an automobile manufacturing enterprise in Guangzhou. Methods Noise-exposed workers from an automobile manufacturer in Guangzhou who underwent occupational health examination in Guangzhou Occupational Disease Prevention and Treatment Hospital from January to December 2018 were selected as the study subjects. The subjects were examined by pure tone threshold test, noise exposure level test and questionnaire survey, then the cumulative noise exposure was calculated, and the correlation between each factor and the occurrence of different frequency hearing loss was analyzed by univariate and multivariate Logistic regressions. Results All 2 605 noise-exposed workers were male and Han nationality, 22 （20, 24） years old, working for 3 （1,4） years, and the noise exposure intensity was 83.50 （82.10, 86.10） dB（A）, cumulative noise exposure was 87.97 （85.11, 90.81） dB（A）·year.The detection rate of hearing loss was 34.40% （896/2 605）. There were no statistically significant difference in the detection rates of hearing loss, whisper frequency and high frequency hearing loss between left and right ears （P>0.05）.The detection rates of hearing loss in both left and right ears increased with the increase of frequency （trend χ²=1 111.38, 1 237.14, P<0.01）,and the highest detection rate was at 6.0 kHz in both left and right ears.Multivariate Logistic regression showed that no significant correlation between smoking, drinking and hearing loss at all frequencies （P>0.05）.With the increase of cumulative noise exposure（OR values of 0.5-6.0 kHz were 3.231, 4.151, 4.809, 3.282, 2.735, 2.069, respectively）or age（OR values of 0.5-6.0 kHz were 2.167, 2.323, 2.508, 1.776, 1.414, 1.276, respectively）, the detection rate of hearing loss of each frequency gradually increased （P<0.05）. Conclusion The hearing loss of noise-exposed workers in automobile manufacturing enterprises with different frequencies is more significant at 6.0 kHz, and there is a dose-response relationship between cumulative noise exposure, age and hearing loss at each frequency.

Key words: Noise exposure, Hearing loss, Dose-response relationship