Abstract: Objective To investigate the cognitive level of the human papillomavirus (HPV) and its vaccine, as well as the related influencing factors among the male population in Liuzhou City. Methods A convenience sampling method was used to collect basic information and knowledge about HPV and vaccines from 2 402 men in Liuzhou City through a self-administered online questionnaire. Chi-square, t-test, and binary Logistic regression methods were used to analyze the cognition of survey subjects towards HPV and its vaccines, as well as their influencing factors. Results A total of 2 402 men in Liuzhou City were included, with an average age of (27.43±7.07) years. The average awareness rate of HPV knowledge was 61.55% (7 392/12 010). Binary logistic regression analysis revealed that sexual history (OR=2.04), HPV infection history (OR=1.98), marital status (OR=2.50 for single, OR=2.24 for married/cohabiting), Objective support for social relationships (OR=1.15), support availability (OR=1.15), sexual orientation (OR=0.60 for gay, OR=0.20 for bisexual), and occupation (OR=0.64 for migrant workers) were the factors influencing the cognitive level (all P<0.05). Conclusions Male population in Liuzhou City has a high cognitive level of HPV and its vaccine. In daily publicity work, attention should be paid to the influence of social relations, peer education, and other factors on the cognition of the survey subjects. Socially vulnerable groups such as migrant workers, gay or bisexual, and divorced or widowed people have low awareness of relevant knowledge, and are key groups for publicity of relevant knowledge in the future.

Key words: HPV vaccine, Male, Cognitive level, Influencing factor