上海市发热儿童病例热性惊厥发生状况及影响因素分析

doi:10.12183/j.scjpm.2021.1250

摘要/Abstract

摘要： 目的分析发热儿童病例热性惊厥的发生状况和影响因素,为预防发热儿童发生热性惊厥提供科学依据。方法采用前瞻性方法对上海市某医院2019年1月至2020年12月发热儿童病例的热性惊厥发生情况及影响因素进行研究。结果本研究共纳入29 825例发热儿童进行分析,其中男17 377例,女12 448例,男女性别比为1.4∶ 1,年龄5个月~12岁,平均（5.02± 1.64）岁,体温高峰38.5 ℃~39.6 ℃,平均（39.08± 0.21）℃。发热儿童发生252例热性惊厥,发生率为0.84%。多因素Logistic回归分析结果显示,年龄3~<6岁（OR=0.879）、6~12岁（OR=0.326）、男童（OR=1.219）、早产（OR=1.553）、体温高峰>39 ℃（OR=5.801）、有热性惊厥家族史（OR=3.155）、特定疫苗接种后2周内（OR=1.486）、小细胞低色素贫血（OR=5.425）、低血钙（OR=4.632）、低血钠（OR=4.473）是发热儿童发生热性惊厥的影响因素。结论发热儿童有热性惊厥发生风险,造成发热儿童发生热性惊厥的影响因素较多,应针对上述危险因素采取应对措施,以减少热性惊厥的发生。

关键词: 发热儿童, 热性惊厥, 影响因素

Abstract: Objective To analyze the incidence and influencing factors of febrile convulsion （FC） in febrile children, so as to provide scientific basis for preventing FC in febrile children. Methods The incidence and influencing factors of FC in febrile children in a hospital in Shanghai from January 2019 to December 2020 were studied by prospective method. Results A total of 29 825 febrile children were included in this study, including 17 377 boys and 12 448 girls. The boy to girl ratio was 1.4∶1. The age ranged from 5 months to 12 years, with an average of （5.02±1.64） years. The peak temperature was 38.5 ℃~ 39.6 ℃, with an average of （39.08±0.21）℃. Two hundred and fifty-two FC occurred in febrile children, and the incidence rate of FC was 0.84%. Multivariate Logistic regression analysis showed that aged 3-<6 years （OR=0.879）, aged 6-12 years （OR=0.326）, boy （OR=1.219）, premature delivery （OR=1.553）, peak body temperature>39 ℃ （OR=5.801）, a family history of FC （OR=3.155）, within 2 weeks after specific vaccination （OR=1.486）, hypochromic microcytic anemia （OR=5.425）, hypocalcemia （OR=4.632）, hyponatremia （OR=4.473） were influencing factors for FC in febrile children. Conclusion Febrile children are at risk of FC, and there are many influencing factors. Countermeasures should be taken against the above risk factors to reduce the incidence of FC.

Key words: Febrile children, Febrile convulsion, Influencing factor

中图分类号:

R195.4

徐晶,王瑞琪,许莉莉. 上海市发热儿童病例热性惊厥发生状况及影响因素分析[J]. 华南预防医学, 2021, 47(10): 1250-1253.

XU Jing, WANG Rui-qi, XU Li-li. Incidence and influencing factors of febrile convulsion in febrile children in Shanghai[J]. South China Journal of Preventive Medicine, 2021, 47(10): 1250-1253.

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