体检人群胃食管反流病患病情况及相关因素研究

doi:10.12183/j.scjpm.2022.1319

摘要/Abstract

摘要： 目的了解青岛市市立医院体检人群胃食管反流病的患病情况及相关的影响因素。方法选择2019年1月1日至2021年12月31日在青岛市市立医院进行健康体检的人群作为研究对象,采用问卷调查方法对健康体检人群进行资料收集,对具有烧心或反流症状者进一步采用《胃食管反流病量表》进行胃食管反流病筛查,采用质子泵抑制剂试验方法完成胃食管反流病确诊过程。采用描述性分析方法对体检人群胃食管反流病发生情况进行分析,并采用单、多因素分析方法对胃食管反流病影响因素进行分析。结果共有16 398人在医院接受体检,其中男性7 568人,女性8 830人,年龄23~76岁,以45~59岁年龄段所占比例最高,为40.79%。共有864例诊断为胃食管反流病,患病率为5.27%。多因素Logistic回归分析结果显示,年龄≥; 45岁（OR=1.936、2.106）、女性（OR=3.086）、BMI<18.5、≥; 24.0 kg/m²（OR=1.102、1.066、1.084）、有饭后平躺习惯（OR=1.554）、喜食油腻（OR=1.335）、吸烟（OR=5.900）、饮酒（OR=3.861）、焦虑（OR=2.021）的体检人群具有更高的胃食管反流病患病风险。结论青岛地区体检人群具有一定的胃食管反流病患病风险,该人群胃食管反流病的影响因素同我国其他人群的相似,在实际工作中需对这些因素进行重点关注。

关键词: 体检人群, 胃食管反流病, 食管, 消化道黏膜, 油腻

Abstract: Objective To understand the prevalence and related influencing factors of gastroesophageal reflux disease (GERD) in physical examinees in Qingdao Municipal Hospital. Methods The physical examinees of Qingdao Municipal Hospital from January 1, 2019 to December 31, 2021 were selected, and data were collected by questionnaire. The patients with heartburn or reflux symptoms were further screened for GERD using the Gastroesophageal Reflux Disease Scale, and the proton pump inhibitor test was used to diagnose GERD. The descriptive analysis method was used to analyze the occurrence of GERD in the physical examinees, and univariate and multivariate analysis methods were used to analyze the influencing factors of GERD. Results A total of 16 398 people received physical examination in the hospital, including 7 568 males and 8 830 females, aged 23-76, with the highest proportion of 45-59 years, accounting for 40.79%. There were 864 cases of GERD, and the prevalence rate was 5.27%. Multivariate Logistic regression analysis showed that the physical examinees with age ≥ 45 (OR＝1.936,2.106), female (OR＝3.086), body mass index＜18.5,≥24.0 kg/m² (OR＝1.102, 1.066, 1.084), lying flat after meals (OR＝1.554), liking greasy food (OR＝1.335), smoking (OR＝5.900), drinking (OR＝3.861), and anxiety (OR＝2.021) had a higher risk of GERD. Conclusions The physical examinees of Qingdao City have a certain risk of GERD. The influencing factors of GERD in physical examinees are similar to those in other populations in China, we can focus on these factors in practical work.

Key words: Physical examinees, Gastroesophageal reflux disease, Esophagus, Gastrointestinal mucosa, Greasy

中图分类号:

R195

葛少莉, 王慧敏, 栾桂萍. 体检人群胃食管反流病患病情况及相关因素研究[J]. 华南预防医学, 2022, 48(11): 1319-1322.

GE Shao‐li, WANG Hui‐min, LUAN Gui‐ping. Prevalence and related factors of gastroesophageal reflux disease in physical examinees[J]. South China Journal of Preventive Medicine, 2022, 48(11): 1319-1322.

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