广州市小作坊生产散装土榨花生油黄曲霉毒素B1污染状况及暴露评估

doi:10.12183/j.scjpm.2023.0132

华南预防医学 ›› 2023, Vol. 49 ›› Issue (2): 132-136.doi: 10.12183/j.scjpm.2023.0132

广州市小作坊生产散装土榨花生油黄曲霉毒素B₁污染状况及暴露评估

王燕燕, 陈坤才, 刘于飞, 李燕, 林晓华, 张玉华, 张维蔚

广州市疾病预防控制中心,广东广州 510440

收稿日期:2022-03-08 出版日期:2023-02-20 发布日期:2023-04-28
通讯作者: 张维蔚,E-mail:249726849@qq.com
作者简介:王燕燕（1990—）,女,硕士研究生,主管医师,主要从事食品安全风险监测与评估工作
基金资助:
广州市科技计划重点项目（202103000039）; 广州市科技计划一般项目（201904010219）; 广州市卫生健康科技项目（20211A010051）

Contamination level and exposure assessment of aflatoxin B₁ in loose-packed peanut oil extracted by a native method in individual workshops in Guangzhou

WANG Yan-yan, CHEN Kun-cai, LIU Yu-fei, LI Yan, LIN Xiao-hua, ZHANG Yu-hua, ZHANG Wei-wei

Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China

Received:2022-03-08 Online:2023-02-20 Published:2023-04-28

摘要/Abstract

摘要： 目的了解2016—2021年广州市本地小作坊生产散装土榨花生油黄曲霉毒素B₁污染状况,并对土榨花生油消费人群健康风险及肝癌风险进行评估。方法对2016—2021年广州市采集的203份本地小作坊生产散装土榨花生油采用高效液相色谱-荧光法/柱后衍生法测定样品中黄曲霉毒素B₁的含量,结果按照《食品安全国家标准食品中真菌毒素限量》（GB 2761）进行评价。基于概率评估理论,分别运用暴露限值（MOE）和数学模型法对土榨花生油消费人群的健康风险及肝癌风险进行评估。结果 203份土榨花生油黄曲霉毒素B₁检出率为76.85% （156/203）,超标率为9.85% （20/203）。2019—2021年各年度黄曲霉毒素B₁检出均值及最大值较2016—2018年有所下降。健康风险评估结果显示,各年龄段土榨花生油消费人群MOE值均<10 000,且高消费人群因土榨花生油黄曲霉毒素B₁导致的肝癌风险均大于1例癌症/（100万人·年）。结论广州市小作坊生产散装土榨花生油黄曲霉毒素B₁污染情况有所改善,但土榨花生油消费人群暴露于土榨花生油黄曲霉毒素B₁的健康风险仍值得关注,建议进一步加强土榨花生油小作坊监督监管力度。

关键词: 土榨花生油, 黄曲霉毒素B₁, 特色食品, 暴露评估

Abstract: Objective To investigate the contamination level of aflatoxin B₁ in loose-packed peanut oil extracted by a native method in individual workshops in Guangzhou from 2016 to 2021, and to evaluate the corresponding health risk and liver cancer risk of loose-packed peanut oil consumers. Methods In 2016-2021, a total of 203 loose-packed peanut oil extracted by a native method in individual workshops were collected in Guangzhou. Aflatoxin B₁ concentrations were examined by HPLC-fluorometry and HPLC-post-chromatographic derivatization photometry, and evaluated according to the National Food Safety Standard-Limit of Mycotoxins in Food （GB 2761）. Based on the probability assessment theory, methods of margin of exposure （MOE） and mathematical model were used to evaluate the health risk and liver cancer risk of loose-packed peanut oil consumers. Results The detection rate and over-standard rate of aflatoxin B₁ in 203 loose-packed peanut oil were 76.85% （156/203） and 9.85% （20/203）, respectively. The mean and maximum detection values in 2019-2021 were lower than those in 2016-2018. The results of the health risk assessment showed that the MOE values of peanut oil consumers of all ages were bellowed 10 000, and the risk of liver cancer caused by aflatoxin B₁ in high consumption groups was greater than 1 cancer / （1 million people/year）.Conclusions The contamination level of aflatoxin B₁ in loose-packed peanut oil extracted by a native method in individual workshops in Guangzhou has been improved. While the health risk of peanut oil consumers exposed to aflatoxin B₁ in peanut oil still deserves attention. It is suggested to further strengthen the supervision of individual workshops on peanut oil.

Key words: Peanut oil extracted by native method, Aflatoxin B₁, Specialty food, Exposure assessment

中图分类号:

R155

王燕燕, 陈坤才, 刘于飞, 李燕, 林晓华, 张玉华, 张维蔚. 广州市小作坊生产散装土榨花生油黄曲霉毒素B₁污染状况及暴露评估[J]. 华南预防医学, 2023, 49(2): 132-136.

WANG Yan-yan, CHEN Kun-cai, LIU Yu-fei, LI Yan, LIN Xiao-hua, ZHANG Yu-hua, ZHANG Wei-wei. Contamination level and exposure assessment of aflatoxin B₁ in loose-packed peanut oil extracted by a native method in individual workshops in Guangzhou[J]. South China Journal of Preventive Medicine, 2023, 49(2): 132-136.

参考文献

[1] 杨朝慧,吴炜亮,张朵,等. 2015—2020年我国食用植物油质量安全风险因素分析[J].中国油脂,2021, 46(12): 69-78.
[2] 荆丹,岳晓凤,白艺珍,等.黄曲霉对花生和玉米的侵染研究[J].中国油料作物学报,2022,44(2):442-450.
[3] 徐文静,刘丹,韩小敏,等. 2015年我国部分地区市售食用植物油中黄曲霉毒素污染调查[J].中国食品卫生杂志,2018,30(1): 63-68.
[4] 胡振,周芳华,韦波. 2016—2017年广西食用植物油质量安全监测评价分析[J].中国油脂,2020, 45(2): 91-94.
[5] 卢宇芳,陈杰,刘银品. 2015年广西部分城市餐饮环节食用植物油中黄曲霉毒素B₁检测结果分析[J].应用预防医学,2018, 24(4): 307-308.
[6] 范云燕,欧嵩凤.中国食用植物油中黄曲霉毒素B₁污染现状及风险评估研究进展[J].职业与健康,2020, 36(5): 701-705.
[7] Rogers AE, Newberne PM.Nutrition and aflatoxin carcinogenesis[J].Nature,1971, 229(5279): 62-63.
[8] 吴基任,潘望,谭高好,等. 2021年海南省小作坊土榨花生油中黄曲霉毒素B₁的调查分析[J].食品安全导刊,2021,325(32):106-109.
[9] 丁小霞,李培武,白艺珍,等.中国花生黄曲霉毒素风险评估中膳食暴露非参数概率评估方法[J]. 中国油料作物学报,2011, 33(4): 402-408.
[10] 中华人民共和国国家卫生和计划生育委员会,国家食品药品监督管理总局.GB 2761—2017食品安全国家标准食品中真菌毒素限量[S].北京:中国标准出版社,2017.
[11] 田洪芸,王爱竹,冯炜,等.市售土榨花生油黄曲霉毒素监测结果及监管建议[J].安徽农业科学,2016, 44(11): 101-102.
[12] 中华人民共和国国家卫生和计划生育委员会,国家食品药品监督管理总局. GB 5009.22—2016食品安全国家标准食品中黄曲霉毒素B族和G族的测定[S].北京:中国标准出版社,2016.
[13] 宋美英,乐丽华,罗钰珊,等.广东小作坊生产花生油中黄曲霉毒素B₁膳食暴露及风险评估[J]. 中国油脂,2019, 44(4): 96-101.
[14] 李可,丘汾,蒋立新,等.深圳地区人群粮油食品中黄曲霉毒素膳食暴露评估[J].卫生研究,2014, 43(4): 630-636.
[15] Evaluation of certain food additives and contaminants. Forty-ninth report of the Joint FAO/WHO Expert Committee on Food Additives[J]. World Health Organ Tech Rep Ser,1999, 884:1-96.
[16] Joint FAO/WHO Expert Committee on Food Additives. Evaluation of certain food contaminants: Sixty-fourth report of the Joint FAO/WHO Expert Committee on Food Additives[J]. World Health Organ Tech Rep Ser,2015,930(3):1-99, back cover.
[17] EFSA Panel on Contaminants in the Food Chain (CONTAM), Schrenk D, Bignami M, et al. Risk assessment of aflatoxins in food[J]. EFSA J,2020: 18(3):e06040.
[18] 周少君,黄湘东,汪廷彩,等.广东省常见发酵茶中黄曲霉毒素B₁污染现状及暴露评估[J].中国食品卫生杂志,2018,30(1): 93-98.
[19] Authority EFS.Opinion of the Scientific Committee on a request from EFSA related to a harmonised approach for risk assessment of substances which are both genotoxic and carcinogenic[J]. EFSA J, 2005, 3(10): 1-31.
[20] 肖潇,隋海霞.食品中遗传毒性致癌物风险评估方法研究[J].中国食品卫生杂志,2018,30(4): 425-429.
[21] 李可,陈网璇,丘汾,等.非参数概率法评估2015—2017年深圳地区9类食品黄曲霉毒素膳食暴露风险[J].卫生研究,2018, 47(5): 827-832.
[22] 梁剑,邵晓萍,吴承刚,等.广东省乙型病毒性肝炎表面抗原携带率的变化分析[J].华南预防医学,2011, 37(4): 40-42.
[23] 王绪卿,吴永宁,陈君石.食品污染监测低水平数据处理问题[J].中华预防医学杂志,2002(4): 63-64.
[24] 张毅,林肖惠,夏义平,等. 2017年天津市市售植物油部分真菌毒素污染状况[J].职业与健康,2018, 34(24):3353-3356.
[25] 程恒怡,钟延旭,陈杰,等.广西居民食用植物油黄曲霉毒素B₁膳食暴露评估[J].应用预防医学,2017, 23(6): 451-454.
[26] 叶艺娟,陈俏嫦,黄振波,等.河源市市售食用植物油污染状况调查分析[J].中国卫生检验杂志,2020, 30(20): 2532-2534.
[27] 杨博磊,张秀娟,王刚,等.我国土榨花生油黄曲霉毒素B₁及圆弧偶氮酸毒素污染调查[J].中国油脂,2020, 45(9): 34-37.
[28] 黄少文,罗辉平,曾小平,等.清远市小作坊花生油中黄曲霉毒素B₁暴露风险评估[J].食品安全导刊,2019(21): 66-67.
[29] 李亚,梁剑锋,柯立坚,等.梧州市土榨花生油中黄曲霉毒素B₁膳食暴露风险评估[J].中国油脂,2022,47(11):80-84.
[30] 耿梦梦,徐明芳,王阳,等.基于Monte Carlo模拟法对液态乳中黄曲霉毒素M₁的风险评估[J].食品科学,2018, 39(5): 226-233.

广州市小作坊生产散装土榨花生油黄曲霉毒素B₁污染状况及暴露评估

Contamination level and exposure assessment of aflatoxin B₁ in loose-packed peanut oil extracted by a native method in individual workshops in Guangzhou

PDF (PC)

赞

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 1

Metrics

本文评价

推荐阅读 0