新疆生产建设兵团饮水型地方性氟中毒病区调查结果及氟化物的非致癌健康风险评估

doi:10.12183/j.scjpm.2023.0553

华南预防医学 ›› 2023, Vol. 49 ›› Issue (5): 553-557.doi: 10.12183/j.scjpm.2023.0553

新疆生产建设兵团饮水型地方性氟中毒病区调查结果及氟化物的非致癌健康风险评估

王文瑾¹, 马晓玲², 李凡卡²

1.石河子大学医学院,新疆石河子 832000;
2.新疆生产建设兵团疾病预防控制中心

收稿日期:2022-06-28 出版日期:2023-05-20 发布日期:2023-08-10
通讯作者: 李凡卡,E-mail：lifanka@sina.com
作者简介:王文瑾（1996—）,女,在读硕士研究生,从事地方病流行病学研究工作
基金资助:
新疆生产建设兵团疾病预防控制中心自主课题（BTCDCKY202204）

Survey results of drinking water-type endemic fluorosis in Xinjiang Production and Construction Corps and non-carcinogenic health risk assessment of fluoride

WANG Wenjin¹, MA Xiaoling², LI Fanka²

1. School of Medicine, Shihezi University, Shihezi 832000, China;
2. Xinjiang Production and Construction Corps Center of Disease Control and Prevention

Received:2022-06-28 Online:2023-05-20 Published:2023-08-10

摘要/Abstract

摘要： 目的了解新疆生产建设兵团（以下简称兵团）饮水型地方性氟中毒防治现状,评估饮用水中氟化物非致癌健康风险。方法 2019年对兵团所有饮水型氟中毒病区进行监测,包括11个师,62个团场,监测内容为改水工程运行状况、水氟含量及8~12岁儿童氟斑牙患病情况,采用美国环保局（US EPA）的风险评估模型对经饮水途径摄入氟化物健康风险进行评估。结果兵团饮水型氟中毒病区团场城镇改水率100.00%（62/62）,改水工程100.00%正常运转,水氟含量为0.09~1.94 mg/L,水氟合格率96.77%（60/62）;农牧连队改水率100.00%（611/611）,水氟含量为0.01~7.27 mg/L,水氟合格率为90.02%（550/611）;总合格率为90.64%（610/673）。儿童氟斑牙患病率为3.65%（1 564/42 839）,氟斑牙指数0.07,无氟斑牙流行,各师患病率差异有统计学意义（P<0.01）,十四师氟斑牙患病率最高,为11.48%;男性和女性均为6~<9岁组氟化物非致癌健康风险危害系数最高,分别为0.29和0.30。结论兵团饮水型氟中毒病区改水率高,儿童氟斑牙病情已得到控制,但个别团场城镇和农牧连队水氟仍存在超标,仍需加强改水工程的监管和水氟含量的监测。

关键词: 兵团, 饮水型氟中毒, 氟斑牙, 氟化物, 健康风险评估

Abstract: Objective To understand the current situation of prevention and treatment of drinking water-type endemic fluorosis in Xinjiang Production and Construction Corps （hereinafter referred to as the Corps）, and to assess the non-carcinogenic health risk of fluoride in drinking water. Methods In 2019, all drinking water fluorosis areas in the Corps were monitored, including 11 divisions and 62 regiments. The monitoring contents included the operation of the water improvement project, the fluoride content in the water, and the prevalence of dental fluorosis among children aged 8 to 12 years. The risk assessment model of the United States Environmental Protection Agency （US EPA） was used to assess the health risk of fluoride intake through drinking water. Results In the regimental towns of drinking water-type fluorosis area, the water improvement rate was 100.00% （62/62）, the water improvement project was 100.00% in normal operation, the water fluoride content was 0.09 - 1.94 mg/L, and the qualified rate was 96.77% （60/62）; The water improvement rate of the farming and animal husbandry company was 100.00% （611/611）, the water fluoride content was 0.01-7.27 mg/L, and the qualified rate was 90.02% （550/611）; The total qualified rate was 90.64% （610/673）. The prevalence rate of dental fluorosis in children was 3.65% （1 564/42 839）, the dental fluorosis index was 0.07, and there was no epidemic of dental fluorosis. There was a statistically significant difference among divisions （P<0.01）. The prevalence rate of dental fluorosis in the 14th division was the highest （11.48%）; The non-carcinogenic health risk hazard coefficients of fluoride in both males and females aged 6 to 9 years were the highest, which were 0.29 and 0.30 respectively. Conclusions The water improvement rate of the drinking water-type fluorosis area of the Corps is high, the condition of children's dental fluorosis has been controlled. However, the water fluoride in some regimental towns and agricultural and animal husbandry companies still exceeds the standard, so it is necessary to strengthen the supervision of water improvement projects and the monitoring of water fluoride content.

Key words: Corps, Drinking water-type fluorosis, Dental fluorosis, Fluoride, Health risk assessment

中图分类号:

R123.1

王文瑾, 马晓玲, 李凡卡. 新疆生产建设兵团饮水型地方性氟中毒病区调查结果及氟化物的非致癌健康风险评估[J]. 华南预防医学, 2023, 49(5): 553-557.

WANG Wenjin, MA Xiaoling, LI Fanka. Survey results of drinking water-type endemic fluorosis in Xinjiang Production and Construction Corps and non-carcinogenic health risk assessment of fluoride[J]. South China Journal of Preventive Medicine, 2023, 49(5): 553-557.

参考文献

[1] 马品江, 王琛琛, 夏荣香, 等. 新疆地方病防治历程回顾与展望[J]. 疾病预防控制通报, 2020,35(3):86-89.
[2] 杨杨,蒋继勇,李生团,等.1997—2001年新疆地方性氟中毒病监测结果分析[J].地方病通报,2003,18(3):86-87.
[3] 王骋,张微,赵丽军,等.2010年全国饮水型地方性氟中毒监测报告[J].中华地方病学杂志,2012,31(4):412-418.
[4] Yuan L, Fei W, Jia F, et al.Health risk in children to fluoride exposure in a typical endemic fluorosis area on Loess Plateau, north China, in the last decade[J]. Chemosphere, 2020,243:125451.
[5] 段小丽. 中国人群暴露参数手册(儿童卷)概要[M].北京:中国环境出版社,2016.
[6] 环境保护部.中国人群暴露参数手册(成人卷)[M].北京:中国环境出版社,2013.
[7] United States Environment Protection Agency.Integrated risk information systerm[EB/OL].(1987-01-31)[2022-7-15].https://cfpub.epa.gov/ncea/iris_drafts/atoz.cfm.
[8] 高彦辉. 我国地方性氟中毒防治70年成就与经验[J].中华地方病学杂志,2019,38(9):689-691.
[9] 范淑玲. “十三五”期间我国地方性氟中毒防制现状[J]. 环境与职业医学, 2020,37(12):1219-1223.
[10] 裴俊瑞, 赵丽军, 张微, 等. 2012年度全国饮水型地方性氟中毒监测报告[J]. 中华地方病学杂志, 2015,34(9):680-684.
[11] 赵丽军, 裴俊瑞, 张微, 等. 中国2013年度饮水型地方性氟中毒监测[J]. 中华流行病学杂志, 2016,37(6):816-820.
[12] 原春生, 余波, 马嘉俊, 等. 2019年河南省饮水型地方性氟中毒病区监测结果分析[J]. 中华地方病学杂志, 2021,40(9):733-737.
[13] 兰莺, 陈志辉, 叶莺. 2019年福建省饮水型地方性氟中毒病情监测结果分析[J]. 中华地方病学杂志, 2021,40(3):205-210.
[14] Sezgin BI, Onur SG, Mentes A, et al.Two-fold excess of fluoride in the drinking water has no obvious health effects other than dental fluorosis[J]. J Trace Elem Med Biol, 2018,50:216-222.
[15] 魏宏,白润本,杨瑞英,等.2002年新疆农三师地方性氟中毒调查报告[J].地方病通报,2005,20(2):35-37.
[16] 熊光,陈安.2006年新疆兵团农一师饮水型地方性氟中毒调查[J].农垦医学,2008,30(4):299-301.
[17] 黄金明, 马玉琴, 任颖, 等. 2019年山东省饮水型地方性氟中毒病区监测结果分析[J]. 中华地方病学杂志, 2021,40(2):114-117.
[18] 阚忠媛, 王健辉. 辽宁省饮水型地方性氟中毒病区儿童氟斑牙普查结果分析[J]. 现代预防医学, 2021,48(19):3499-3502.
[19] 高彦辉. 大力推进地方性氟中毒的精准防控工作[J]. 中华地方病学杂志, 2017,36(2):87-89.
[20] Zhang L, Zhao L, Zeng Q, et al.Spatial distribution of fluoride in drinking water and health risk assessment of children in typical fluorosis areas in north China[J]. Chemosphere, 2020,239:124811.
[21] Zhang LE, Huang D, Yang J, et al.Probabilistic risk assessment of Chinese residents' exposure to fluoride in improved drinking water in endemic fluorosis areas[J]. Environ Pollut, 2017,222:118-125.

新疆生产建设兵团饮水型地方性氟中毒病区调查结果及氟化物的非致癌健康风险评估

Survey results of drinking water-type endemic fluorosis in Xinjiang Production and Construction Corps and non-carcinogenic health risk assessment of fluoride

PDF (PC)

赞

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 4

Metrics

本文评价

推荐阅读 0

[1]	曹立春, 穆小瑜, 李文凤. 天津市北辰区饮水型氟中毒改水监测结果分析[J]. 华南预防医学, 2021, 47(10): 1348-1350.
[2]	杨柳小溪, 姚钰, 马文霞, 孙俊俊. 2019—2020年西安市高氟地区学龄儿童氟斑牙和龋齿现状及其影响因素[J]. 华南预防医学, 2021, 47(10): 1236-1240.
[3]	杨通，刘礼平，钟文，温妍，池海珊. 2015年广东省饮水型地方性氟中毒监测结果分析[J]. 华南预防医学, 2016, 42(5): 482-483.
[4]	赵岩，冯利红，李建平，王玉雯，刘洪亮. 天津市冬季PM2.5中多环芳烃来源及健康风险评价[J]. 华南预防医学, 2016, 42(1): 25-31.