珠海市老年女性骨质疏松性骨折危险因素调查

doi:10.13217/j.scjpm.2019.0401

摘要/Abstract

摘要： 目的分析珠海市老年女性骨质疏松性骨折的影响因素,为降低老年女性骨折发生风险提供依据。方法采用简单抽样方法分别抽取珠海市50~70岁女性骨质疏松性骨折病例为病例组、健康体检女性为对照组进行问卷调查,调查内容包括人口学特征、年龄、婚姻状态、家庭收入、文化程度、户外活动量、BMI、月经初潮年龄、绝经年龄、怀孕次数、生产胎儿数、骨折史、饮酒史、吸烟史、牛奶摄入频率等。采用单、多因素分析方法对影响该年龄段女性骨质疏松性骨折发生因素进行分析。结果本研究共纳入200例50~70岁女性骨质疏松性骨折患者作为病例组和200名50~70岁健康女性为对照组。病例组和对照组人群均以60~70岁为主,分别占75.0%、66.5%,婚姻状态以已婚为主,分别占80.0%、85.0%。家庭月收入<5 000元分别占60.0%、55.0%,文化程度均以大专及以上为主,分别占60.0%、57.5%。有骨折史（OR=4.116）、有吸烟史（OR=3.904）和绝经年龄<45岁（OR=4.229）是50~70岁女性发生骨质疏松性骨折的危险因素,户外活动量≥60 min/d（OR=0.417）、牛奶摄入频率≥3次/周（OR=0.191）是该年龄段女性骨折疏松性骨折的保护因素。结论户外活动量、骨折史、吸烟史、牛奶摄入频率和绝经年龄是50~70岁女性骨质疏松性骨折发生的影响因素,户外活动量较大、牛奶摄入频率较高可降低女性骨质疏松性骨折的发生风险。

关键词: 骨质疏松, 老年女性, 骨折, 影响因素

Abstract: Objective To explore risk factors of osteoporotic fracture in elderly women in Zhuhai in 2017.Methods A simple sampling method was used to select female patients with osteoporotic fractures aged 50-70 years in Zhuhai City as a case group and healthy women who underwent a physical examination as a control group to conduct a questionnaire survey. The survey contents included demographic characteristics, age, marital status, family income, education, outdoor activities, BMI, menarche age, menopausal age, number of pregnancies, number of fetuses, history of fractures, history of drinking, history of smoking, frequency of milk intake, etc. Univariate and multivariate logistic regressions were used to determine the factors affecting osteoporotic fractures in this age group.Results A total of 200 women aged 50-70 years with osteoporotic fractures were included in the study as the case group and 200 healthy women aged 50-70 years as the control group. In the case group, 75.0% were aged 60-70 years, 80.0% were married, 60.0% had family monthly income of less than 5 000 Yuan, and 60.0% had the educational level at junior college or above; in the control group, 66.5% were aged 60-70 years, 85.0% were married, 55.0% had family monthly income of less than 5 000 Yuan, and 57.5% had the educational level at junior college or above. The multivariate logistic regression showed that the history of fracture （OR=4.116）, history of smoking （OR=3.904）, and menopausal age <45 years （OR=4.229） were risk factors for osteoporotic fractures in women aged 50-70 years; while the amount of outdoor activity ≥60 min /day （OR=0.417） and milk intake frequency ≥3 times/week （OR=0.191） were protective factors for female fractures of this age group.Conclusion Outdoor activity, fracture history, smoking history, milk intake frequency and menopausal age are the influencing factors of osteoporotic fracture in women aged 50-70 years. The large amount of outdoor activities and high frequency of milk intake can reduce osteoporosis in women.

Key words: Osteoporosis, Elderly women, Fracture, Risk factors

中图分类号:

R173

彭鹏, 林伟基. 珠海市老年女性骨质疏松性骨折危险因素调查[J]. 华南预防医学, 2019, 45(5): 401-405.

PENG Peng, LING Wei-ji. Risk factors of osteoporotic fracture in elderly women in Zhuhai, 2017[J]. South China Journal of Preventive Medicine, 2019, 45(5): 401-405.

参考文献 20

[1]	王熙然,白玉蓉,裴育,等. 北京某社区 40 岁以上女性原发性骨质疏松症流行现状调查[J].中华保健医学杂志,2017,19(2):132-134.
[2]	曹婷,张巧,时立新,等.代谢综合征及其各组分与骨质疏松性骨折的相关性研究[J].中国全科医学,2017,20(8):903-905.
[3]	Oliai AS, van Dijk SC, Ham AC, et al. BMI and body fat mass is inversely associated with vitamin D levels in older individuals[J].Nutr Health Aging, 2015, 19(10):980-985.
[4]	Hossein-nezhad A, Holick MF. Vitamin D for health: a global perspective[J].Mayo Clin Proc, 2013, 88(7):720-755.
[5]	邱贵兴,裴福兴,胡侦明,等.中国骨质疏松性骨折诊疗指南(全文)(骨质疏松性骨折诊断及治疗原则)[J].中华关节外科杂志(电子版),2015,9(6):795-798.
[6]	叶远辉. 骨质疏松骨折后再骨折临床风险分析[J].中外医学研究,2013, 11(7):128.
[7]	蒋军威,陈丽敏,张莹.临床骨质疏松性骨折老年女性患者健康行为及影响因素分析[J].中外女性健康研究,2016(16):232,238.
[8]	郑蔚,张苇,张利霞,等.临床骨质疏松性骨折老年女性患者健康行为及影响因素分析[J].现代预防医学,2014,41(14):2544-2546.
[9]	李洪秋,阿良,赵忠海,等.沈阳地区老年髋部骨质疏松性骨折流行病学调查分析[J].中国骨质疏松杂志,2013,19(3):293-296.
[10]	Iwasaki E, Morakote N, Chaovistsaree S, et al.Bone mineral density and bone turnover among young women in Chiang Mai, Thailand[J].Kobe J Med Sci,2014 ,59(5):E149-E156.
[11]	陈峰,白卫东,孙云伟,等.广州市萝岗区老年性骨质疏松性骨折的流行病学调查和分析[J].中国现代医生,2013, 51(2):13-14.
[12]	乔芳,常静.骨质疏松流行病学调查分析[J].中国实用医药,2012, 7(30):271-272.
[13]	Morrion A, Fan T, Sen SS, et al.Epidemiology of falls and osteoporotic fractures: a systematic review[J].Clinicoecon Outcomes Res, 2013(5):9-18.
[14]	张美娟. 运动疗法对绝经期女性骨质疏松骨折的预防作用[J].中国老年学杂志,2013,33(9):2188-2189.
[15]	时秋宽,石婧. 2008—2013 年中华系列杂志老年人骨质疏松文献分布和现状分析[J]. 中华老年医学杂志,2015,34(4):448-451.
[16]	袁宏,钟惠琴. 全髋关节置换术后联合抗骨质疏松治疗的价值[J]. 中华关节外科杂志(电子版) ,2014,8(3):376-379.
[17]	邢清, 臧丽, 庞萍, 等. Gitelman综合征合并骨质疏松症2例临床分析[J]. 中国热带医学, 2018, 18(11): 1162-1165.
[18]	王溪原,张伟,冯晰民.绝经女性被动吸烟行为对骨密度指标及抗骨折能力影响的调查[J].实用预防医学,2007,14(2):335-337.
	张伟,王兵,张林林,等. 绝经后股骨颈骨折股骨头骨铁含量血清铁蛋白与骨密度相关性研究[J].中华骨科杂志,2014,34(1):39-47.
[19]	蒋建发,孙爱军.中老年女性骨质疏松症的防治[J]. 中国实用妇科与产科杂志,2014,30(5):323-326.
[20]	Kamondetdecha R, PanyakhamLerd K, Chaikittisllpa S, et al.Value of Osteoporosis Self-assessment Tools for Asians (OSTA)with or without Brown ’s clinical risk factors in detection of postmenopausal osteoporosis[J].Climacteric,2013,16(1) :127-132.