华南预防医学 ›› 2020, Vol. 46 ›› Issue (4): 351-354.doi: 10.12183/j.scjpm.2020.0351

• 论著 • 上一篇    下一篇

深圳市龙岗区HIV感染者/AIDS患者死亡情况及影响因素研究

杨永平1, 李晓霞2, 赵锦3, 刘渠2, 谢显清2, 龙清平2   

  1. 1.深圳市龙岗区坪地预防保健所,广东 深圳 518117;
    2.深圳市龙岗区疾病预防控制中心;
    3.深圳市疾病预防控制中心
  • 收稿日期:2020-01-20 出版日期:2020-08-20 发布日期:2020-09-16
  • 通讯作者: 李晓霞,E-mail:164072369@qq.com
  • 作者简介:杨永平(1979—),男,硕士研究生,副主任医师,主要从事疾病控制工作
  • 基金资助:
    深圳市科技计划项目(JCYJ20170303101644483); 深圳市龙岗区科技计划项目(LGKCYLWS2018000076)

Mortality and influencing factors among people living with HIV and AIDS in Longgang District, Shenzhen

YANG Yong-ping1, LI Xiao-xia2, ZHAOJin3, LIU Qu2, XIE Xian-qing2, LONG Qing-ping2   

  1. 1. Preventive Care of Pingdi of Longgang District, Shenzhen 518117, China;
    2. Shenzhen Longgang District Center for Disease Control and Prevention;
    3. Shenzhen Center for Disease Control and Prevention
  • Received:2020-01-20 Online:2020-08-20 Published:2020-09-16

摘要: 目的 了解深圳市龙岗区艾滋病病毒(HIV)感染者/艾滋病(AIDS)患者(简称HIV/AIDS患者)的死亡情况,并分析其相关影响因素。 方法 通过中国疾病预防控制艾滋病综合防治信息系统,选取2010年1月1日至2018年12月31日现住址为深圳市龙岗区的HIV/AIDS患者,按照病例入选标准确定研究对象;应用多因素Cox比例风险模型分析影响死亡的相关因素。 结果 本研究共选取590例HIV/AIDS患者,死亡236例(男性187例,女性49例)。多因素Cox回归分析结果显示,在婚、离异或丧偶者发生死亡的风险分别是未婚者的0.003倍和0.418倍;确诊时为AIDS患者的死亡风险是HIV感染者的9.149倍;异性传播、同性传播和采供血的死亡风险分别是注射吸毒的0.319、0.079和0.004倍;未接受CD4检测者的死亡风险是接受CD4检测者的9.166倍;接受抗病毒治疗者的死亡风险是未接受抗病毒治疗者的0.052倍。 结论 深圳市龙岗区HIV/AIDS患者死亡情况受多种因素影响,接受CD4检测和进行抗病毒治疗能明显降低HIV/AIDS患者死亡风险。提倡早期发现、早期诊断、进一步扩大CD4检测和抗病毒治疗的覆盖面,并加强追踪随访和管理,以降低HIV/AIDS患者死亡率,提高其生存质量。

关键词: 艾滋病病毒, 艾滋病, 死亡, 影响因素

Abstract: Objective To understand the death status of people living with HIV/AIDS and analyze the related influencing factors in Longgang District, Shenzhen. Methods HIV/AIDS patients with current residential address in Longgang District, Shenzhen City from January 1, 2010 to December 31, 2018 were selected through the China information system for HIV/AIDS comprehensive prevention and control. Cox proportional hazard model was used to analyze the factors influencing the death on HIV/AIDS cases. Results A total of 590 HIV/AIDS cases were chosen, including 236 deaths (187 males and 49 females). Multi-factor Cox regression analysis showed that the risk of death in married, divorced or widowed persons was 0.003 time and 0.418 time that in unmarried persons; the mortality risk of AIDS patients at diagnosis was 9.149 times that of HIV-infected persons; the risk of death from heterosexual transmission, homosexual transmission, and blood collection and supply was 0.319, 0.079, and 0.004 times that of injecting drug use, respectively; the risk of death in those who were not tested for CD4 was 9.166 times that in those who were tested; the risk of death in patients receiving antiviral therapy was 0.052 time that in patients without antiviral therapy. Conclusion The mortality of HIV/AIDS cases in Longgang District, Shenzhen City was affected by many factors. Of them, CD4 testing and antiretroviral therapy could effectively reduce the risk of mortality among HIV/AIDS cases.

Key words: HIV/AIDS, Mortality, Influencing factors

中图分类号: 

  • R512.91