社区老年人久坐时间与肌少症患病风险关联研究

doi:10.12183/j.scjpm.2026.0417

摘要/Abstract

摘要： 目的探索社区老年人久坐时间与肌少症患病风险之间的关联,为老年人肌少症的预防提供针对性干预措施。方法以无锡、上海等地连续居住≥6个月、60岁及以上的社区人群为对象,用多阶段分层配额法抽样取480人开展横断面调查。采用国际体力活动问卷短卷（IPAQ-S）调查久坐时间,并评估肌少症患病情况。采用多因素logistic回归模型分析久坐时间与肌少症的关联,并运用限制性立方样条模型（RCS）探索老年人久坐时间与肌少症患病风险之间的剂量—反应关系。结果回收有效问卷496份,有效回收率97.25%,诊断出肌少症91例（18.35%）。久坐时间2~11 h,平均（6.41±2.37）h。多因素logistic回归结果提示,久坐时间≥8 h/d（OR=4.860）、久坐时间6~8 h/d（OR=2.943）仍然是社区老年人肌少症的危险因素（均P<0.01）。RCS分析显示久坐时间与社区老年人肌少症风险呈现非线性的剂量-反应关系（P_{非线性检验}=0.044）,当社区老年人久坐时间>5 h时,肌少症患病风险随久坐时间的增加急剧上升。在不同年龄、性别、体力活动水平亚组中,久坐时间均与肌少症发病风险呈显著正相关（P<0.05）,其中年龄75~80岁（OR=1.396）、女性（OR=1.383）以及无规律运动（OR=1.276）的老年人中久坐时间与肌少症发病风险的关联更强;年龄65~<75岁、男性及有规律运动的老年人中关联相对较弱（OR值分别为1.173、1.171和1.240）。结论社区老年人中肌少症患病率较高,且久坐时间延长是肌少症发生的独立危险因素,当久坐时间>5 h/d后,肌少症发病风险显著增加。

关键词: 老年人群, 久坐时间, 肌少症, 剂量-反应关系

Abstract: Objective To investigate the association between sedentary time and the risk of sarcopenia among community-dwelling older adults, with the aim of providing targeted interventions for the prevention of sarcopenia in this population. Methods A cross-sectional study was conducted utilizing a multistage stratified quota sampling method to recruit 480 community-dwelling adults aged 60 years and older who had resided continuously for at least six months in cities such as Shanghai, Wuxi. The International Physical Activity Questionnaire-Short Form (IPAQ-S) was administered to assess sedentary time, and participants were evaluated for the prevalence of sarcopenia. A multivariate logistic regression model was employed to analyze the association between sedentary time and sarcopenia. Furthermore, a restricted cubic spline (RCS) model was used to explore the dose-response relationship between sedentary time and the risk of sarcopenia. Results A total of 496 valid questionnaires were returned, yielding a response rate of 97.25%. Sarcopenia was diagnosed in 91 participants, corresponding to a prevalence of 18.35%. Sedentary time ranged from 2 to 11 hours, with a mean of (6.41±2.37) hours. Multivariate logistic regression analysis indicated that sedentary time ≥8 h/d (OR=4.860) and 6-8 h/d (OR=2.943) were significant risk factors for sarcopenia in community-dwelling older adults (both P<0.01). The RCS analysis revealed a non-linear dose-response relationship between sedentary time and the risk of sarcopenia (P for non-linearity=0.044). Specifically, the risk of sarcopenia increased sharply with sedentary time exceeding 5 hours per day. In subgroup analyses stratified by age, sex, and physical activity level, a significant positive correlation was consistently observed between sedentary time and sarcopenia risk (P<0.05). The association was more pronounced in individuals aged 75-80 years (OR=1.396), females (OR=1.383), and those with no regular physical activity (OR=1.276). Conversely, the association was comparatively weaker in individuals aged 65-<75 years (OR=1.173), males (OR=1.171), and those who engaged in regular physical activity (OR=1.240). Conclusion The prevalence of sarcopenia is elevated among community-dwelling older adults, and prolonged sedentary time constitutes an independent risk factor for its development. The risk of sarcopenia increases significantly when daily sedentary time surpasses 5 hours.

Key words: Elderly population, Sedentary time, Sarcopenia, Dose-response relationship

中图分类号:

R161.7

孙丽娜, 汪芸玏. 社区老年人久坐时间与肌少症患病风险关联研究[J]. 华南预防医学, 2026, 52(4): 417-421.

Sun Lina, Wang Yunyu. Association between sedentary time and risk of sarcopenia in community-dwelling older adults[J]. South China Journal of Preventive Medicine, 2026, 52(4): 417-421.

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