Abstract: Objective To evaluate the reporting quality of infectious diseases in medical institutions in cities in Guangdong and explore countermeasures to strengthen the reporting quality of medical institutions. Methods Using stratified sampling method, relevant indicators of the reporting quality of infectious disease in medical institutions were obtained through questionnaire survey and spot check. A chi-square test was used to analyze the differences in reporting quality at different levels and regions, Pearson correlation method was used to analyze the correlation between the comprehensive rate of reporting quality and GDP per capita, and weighted rank sum ratio（WRSR） method was adopted to comprehensively evaluate and grade the reporting quality of infectious diseases in 21 prefectural cities. Results During 2017-2019, the reporting quality of infectious diseases of medical institutions in Guangdong Province showed an overall upward trend （P<0. 01）. The reporting qualities of medical institutions at provincial-level were generally superior to those at other levels （P<0. 01）, the Pearl River Delta region was superior to eastern, western and mountainous areas of the province. The comprehensive rate of reporting quality in medical institutions around the province was moderately positively correlated with GDP per capita （r = 0. 608）. Using the WRSR method, 21 prefectural cities were divided into four grades： excellent, good, medium, and poor （P<0. 01）. Conclusion The reporting quality of infectious diseases in different regions of Guangdong Province is uneven, and the reporting rate in western and eastern regions of Guangdong Province has not reached the requirements of the “13th Five-Year Plan”. It is necesary to increasing funding for facilitating the electronic medical record system of medical institutions and strengthen administrative supervision to improve the reporting quality of infectious diseases.

Key words: Reporting quality of infectious diseases, Comprehensive evaluation, Weight rank sum ratio method