Abstract: Objective To understand the prevalence and related influencing factors of gastroesophageal reflux disease (GERD) in physical examinees in Qingdao Municipal Hospital. Methods The physical examinees of Qingdao Municipal Hospital from January 1, 2019 to December 31, 2021 were selected, and data were collected by questionnaire. The patients with heartburn or reflux symptoms were further screened for GERD using the Gastroesophageal Reflux Disease Scale, and the proton pump inhibitor test was used to diagnose GERD. The descriptive analysis method was used to analyze the occurrence of GERD in the physical examinees, and univariate and multivariate analysis methods were used to analyze the influencing factors of GERD. Results A total of 16 398 people received physical examination in the hospital, including 7 568 males and 8 830 females, aged 23-76, with the highest proportion of 45-59 years, accounting for 40.79%. There were 864 cases of GERD, and the prevalence rate was 5.27%. Multivariate Logistic regression analysis showed that the physical examinees with age ≥ 45 (OR＝1.936,2.106), female (OR＝3.086), body mass index＜18.5,≥24.0 kg/m² (OR＝1.102, 1.066, 1.084), lying flat after meals (OR＝1.554), liking greasy food (OR＝1.335), smoking (OR＝5.900), drinking (OR＝3.861), and anxiety (OR＝2.021) had a higher risk of GERD. Conclusions The physical examinees of Qingdao City have a certain risk of GERD. The influencing factors of GERD in physical examinees are similar to those in other populations in China, we can focus on these factors in practical work.

Key words: Physical examinees, Gastroesophageal reflux disease, Esophagus, Gastrointestinal mucosa, Greasy