Abstract: Objective To understand the usage of condoms and related factors among young students engaging in non-regular sexual partner behaviors in Guangdong Province. Methods The research was conducted in 16 universities, technical schools, and vocational colleges in Guangdong Province. The convenient sampling method of non-probability sampling was used to collect information from young students, and their adherence to condom usage during non-regular sexual partner behaviors and related factors were analyzed by logistic regression analysis. Results A total of 1 013 young students engaging in non-regular sexual partner behaviors were surveyed, of them 44.42% （450/1 013） were 16 to 19 years old, 74.73% （757/1 013） were males, 56.76% （575/1 013） reported consistent condom usage during non-regular sexual partner behaviors. The differences in condom usage during non-regular sexual partner behaviors were statistically significant across different genders, school types, average monthly living expenses, only child status, living arrangements on campus, self-reported sexual orientation, stages of AIDS-related health education, AIDS awareness, age of first sexual encounter, use of psychoactive substances during sexual activity in the past year, engaging in regular sexual behaviors and condom usage during such behaviors in the past year （P < 0.05 or P < 0.01）. logistic regression analysis revealed that being an only child （OR=0.623）, use of psychoactive substances during sexual activity in the past year （OR=0.350）, and failure to consistently use condoms during regular sexual partner behaviors in the past year （OR=0.159） were associated with a lower likelihood of using condoms during non-regular sexual partner behaviors; consistently use condoms during regular sexual partner behaviors in the past year （OR=6.845） was associated with a higher likelihood of using condoms during non-regular sexual partner behaviors. Conclusions The proportion of condom usage in non-regular sexual partner behaviors remains low among young students in Guangdong Province. Attention should be paid to only children, those who have used psychoactive substances during sexual activity in the past year, and those engaging in regular sexual partner behaviors but not consistently using condoms. Targeted measures such as propaganda and intervention should be strengthened to enhance their risk awareness and reduce unsafe sexual behavior.

Key words: Young student, Non-regular sexual partner, Sexual behavior, Condom