Abstract: ObjectiveTo identify risk factors of overweight and obesity among employed floating population aged 18-59 years in Guangdong Province and determine intervention measures．MethodsUsing special survey data of China chronic disease and risk factor surveillance for migrant population conducted in 2012, information on cigarette smoking, alcohol consumption, diet, physical activity and health condition among migrant population was collected through face-to-face questionnaire interview and physical examination was performed on the participants. The data were analyzed by univariate and multivariate unconditional logistic regression．ResultsA total of 1 639 floating population , including 889 men (54.2%) and 750 women (45.8%) were surveyed. Of the participants, 62.5% (1 025 / 1 639) had junior high school education level or below, 33.0% were aged 30 to 39 years, and 78.4% were married or cohabited. The prevalence rates of overweight and obesity were 25.4% and 5.9%, and the standardized rates, 23.1% and 5.3%, respectively. In the multiple logistic regression model, the male (OR=1.772）and the married / cohabitated (OR=1.505）were more likely to become overweight and obesity. The possibility of overweight and obesity for other three age groups were 1.565, 2.290 and 2.616 times of that for 18- 29 years age group, and for those whose most of working time was sitting or standing was 2.852 times of that for the heavy manual workers. Respondents with static time for 5 hours or more per day were 1.361 times more likely to be overweight or obese than those with static time for less than 5 hours per day. ConclusionMen, the married / cohabitated, sitting or standing for a long time, and lack of exercise were important risk factors of overweight and obesity for employed floating population aged 18-59 years in Guangdong Province. Health education and physical activity should be enhanced for prevention and control of overweight and obesity.