S China J Prev Med ›› 2015, Vol. 41 ›› Issue (5): 407-411.doi: 10.13217/j.scjpm.2015.0407

• Original Article • Previous Articles     Next Articles

Survival time and related factors among AIDS cases in Lu’an City, 1999-2014

CHEN Haiyan1,2,SU Hong1,MA Gongyan2   

  1. 1.School of Public Health, Anhui Medical University, Hefei 230032,China; 2. Luan Center for Disease Control and Prevention
  • Online:2015-10-20 Published:2015-11-06

Abstract: ObjectiveTo analyze the survival time and related factors of HIV/AIDS in Lu’an City.MethodsData of HIV/AIDS report cards, supplementary cards, case followup tables, medical records and necessary supplementary investigation information of Luan City from 1999 to March 2014 were collected from Chinese national HIV/AIDS comprehensive control and prevention information system, including general demographic characteristics (gender, age, occupation, marital status, educational level), route of infection, stage of disease and CD4 levels at confirmed diagnosis, highly active antiretroviral therapy (HAART) and followup outcome. Life table method was applied to calculate the survival rate. The survival status of the patients was described and the related factors affecting survival status of patients with HIV/AIDS were analyzed by univariate and multivariate logistic regressions.ResultsA total of 661 cases of HIV/AIDS were reported. At the end point of the survey, 540 cases of HIV/AIDS survived and finished the followup, with a survival rate of 81.69%; 121 cases died of AIDS and its associated complications with a death rate of 18.30%. Among them, 512 were males and 149, females; their ages ranged from 1 to 81 years old, with a median age of 34.5 years. The survival rate of HIV/AIDS cases at 1, 3, and 5 years were 83.00%, 80.00%, and 75.00%, respectively. The AIDS related mortality was 6.70/1 000 personmonths. At the end point of the investigation, the 12year survival rate of HIV/AIDS was 67.00%. In the Cox proportional hazard model, compared with the cases of HIV/AIDS with CD4 counts fewer than 100 cells/mm3 at diagnosis, the risk of death was decreased from 0.24 to 0.03 time in the cases with CD4 counts equal or greater than 100 cells/mm 3.The risk of death for cases not receiving HAART was 16.94 times that for cases receiving HAART; compared with the cases aged 60 years and older, the risk of death was decreased from 0.47 to 0.29 time for every 10 years of age in the cases aged 18 years and above at confirmed diagnosis. The risk of death for females was 1.64 times that for males.ConclusionCD4 level and age at confirmed diagnosis and gender influenced the survival time of people living with HIV/AIDS. HAART was one of the effective means to prolong the survival time of AIDS patients; therefore, the coverage of HAART should be further expanded.

CLC Number: 

  • R512.91