美沙酮维持治疗门诊HCV抗体阳性者丙肝治疗影响因素分析

doi:10.12183/j.scjpm.2025.0627

Abstract

Abstract: Objective To understand the influencing factors related to hepatitis C treatment among methadone maintenance treatment (MMT) clinic patients with hepatitis C virus (HCV) antibody positivity, and to provide a basis for formulating effective intervention measures. Methods Using MMT clinics as the research site, a convenient sampling method was used to collect information from HCV antibody-positive individuals in MMT clinics, and their hepatitis C treatment status and influencing factors were analyzed. Results A total of 354 individuals were surveyed, with 334 cases (94.35%) aged 40 and above; 307 cases (86.72%) were male; 351 Han Chinese (99.15%); 194 unemployed individuals (54.80%); 284 with junior high school education or below (80.23%); 176 married or cohabiting (49.72%); and 259 non-single-living individuals (73.16%). 130 cases (36.72%) had received nucleic acid testing for hepatitis C virus, and 110 cases (31.07%) had received anti-HCV treatment. Logistic regression analysis results show that HCV antibody positive patients with a history of alcoholism (OR=2.587), family members aware of the illness (OR=10.644), family members encouraging treatment (OR=2.504), better awareness of hepatitis C knowledge (OR=1.919), having received nucleic acid testing for hepatitis C virus (OR=2.857), and having medical insurance (OR=2.995) were more likely to receive anti-HCV treatment; individuals with HCV antibody positivity engaged in "other" occupations (OR=0.362) have a lower probability of receiving anti-HCV treatment. Conclusion sIn Guangdong Province, the proportion of HCV antibody-positive individuals receiving anti-HCV treatment in MMT clinics is relatively low. To address this issue, the following measures are recommended: strengthen health education to improve patients' awareness of hepatitis C; encourage family involvement in patients' health management and provide necessary support; meanwhile, healthcare institutions should offer accessible nucleic acid testing services to ensure timely diagnosis and treatment for patients.

Key words: Methadone maintenance treatment, HCV antibody positive, Hepatitis C, Influencing factors

CLC Number:

R512.6+3

ZHENG Hongqing, PAN Siyuan, WANG Guoren, WANG Lirong, RUAN Feng, FANG Xiaojun, LI Yan, YANG Fang, LI Jianrong. Analysis of factors influencing hepatitis C treatment in HCV antibody positive patients in methadone maintenance treatment clinics[J].South China Journal of Preventive Medicine, 2025, 51(6): 627-631.

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Analysis of factors influencing hepatitis C treatment in HCV antibody positive patients in methadone maintenance treatment clinics

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