Abstract: Objective To investigate the knowledge, attitude, practice,and demands after returning to school on COVID-19 in college students, so as to provide a basis for the prevention and control in schools. Methods From February 29 to March 5, 2020, an online questionnaire survey was conducted among 7 731 college students in Gansu Province. Descriptive epidemiological analysis was used to analyze the data. Results A total of 7 705 valid questionnaires were collected, with an effective rate of 99.7%. The ratio of male to female students was 1∶3, the ratio of graduate, undergraduate and junior college students was 1∶10∶6, and the ratio of medical students and non-medical students was 4∶1. The average score of COVID-19 cognition was （58.15±13.67）, and the pass rate of cognition was 40.0%. The pass rates of infection source, transmission route, symptoms and protection were 93.9%, 66.4%, 35.7% and 22.2%, respectively. The pass rates of COVID-19 infection source, symptoms and protection in undergraduates were higher than that of junior college students and graduate students （P<0.05）. The cognitive pass rate of medical students was higher than that of non-medical students in terms of infection source and symptoms of COVID-19 （P<0.05）. However, the graduate students paid more attention to the trend of the epidemic, while undergraduates or above were more optimistic about the cure of COVID-19 than junior college students（P<0.01）. The formation rates of wearing masks when going out, covering mouth and nose when coughing or sneezing, not attending parties or going to places with poor air mobility, and frequent ventilation of rooms were all over 90.0%. 78.8% of students were very concerned about the COVID-19 epidemic. After returning to school, respondents' main needs were to provide prevention and control knowledge of COVID-19, stagger the meal times and daily temperature measurement, accounting for 98.0%, 96.7% and 94.9%, respectively. Conclusion College students with different characteristics have large gaps in COVID-19 knowledge, attitude and practice, and have different degrees of vulnerability. Therefore, targeted intervention measures should be taken in combination with individual and school control to prevent and control COVID-19 in schools.

Key words: COVID-19, College student, Knowledge, Attitude, Demand