Abstract: Objective To investigate breast carcinoma-related knowledge, attitude, and practice among hospital nurses in Zhengzhou City and analyze the influencing factors. Methods Taking the nurses from public medical institutions in Zhengzhou as the research object, in March 2021, the nurses from two tertiary hospitals and two secondary hospitals were selected by the convenience sampling method as the survey subjects to carry out a questionnaire on breast carcinoma-related knowledge, attitude, and practice. The descriptive analysis method was used to analyze the breast carcinoma-related knowledge, attitude, and practice of nurses, and univariate and multivariate analysis methods were used to analyze its influencing factors. Results The complete data of 311 nurses were collected. The lowest score for breast carcinoma-related knowledge was 9, and the highest score was 36, with an average of （21.69±5.47）. The lowest score for breast carcinoma-related attitude was 17, and the highest score was 42, with an average of （30.54±5.91）. The lowest score for breast carcinoma-related practice was 3, and the highest score was 14, with an average of （8.94±2.70）. Education background （β'=0.291）, professional title （β'=2.014 ）, department （β'=0.583）, nursing work experience （β'=0.226）, related training （β'=0.765 ）, family history of breast carcinoma （β'=0.180）, and history of breast disease （β'=0.657） were the influencing factors of breast carcinoma-related knowledge. Marital status（married β'=0.309）, department （β'=0.307）, nursing work experience （β'=0.462）, related training （β'=0.479）, family history of breast carcinoma （β'=0.448）, history of breast disease （β'=0.096）, and score of breast carcinoma-related knowledge （β'=1.973） were the influencing factors of breast carcinoma-related attitude. Age （β'=0.565）, marital status （married β'=0.309）, related training （β'=0.126）, family history of breast carcinoma （β'=0.357）, history of breast disease （ β'=0.159）, score of breast carcinoma-related knowledge （β'=2.106）, and score of breast carcinoma-related attitude （ β'=2.231） were the influencing factors of breast carcinoma -related practice. Conclusion The score of breast carcinoma-related knowledge, attitude, and practice of hospital nurses in Zhengzhou City is medium, which is affected by many factors. Targeted interventions should be taken for nurses in different situations to improve their breast carcinoma-related knowledge, attitude, and practice.

Key words: Breast carcinoma, Hospital, Nurse, Knowledge, attitude, and practice