Abstract: Objective To explore the current situation of comorbidities of chronic diseases in Lujiang region,and to provide the reference for optimizing the management of comorbidities of chronic diseases and controlling the occurrence and progression of chronic diseases. Methods A survey and analysis were conducted on chronic disease patients who visited three hospitals in the Lujiang region from January 2021 to December 2023,including general demographic information such as gender and age,exercise status,sleep time,etc. Potential category recognition was used to analyze the comorbidity patterns of chronic diseases,and disordered multivariate Logistic regression analysis was used to analyze the influencing factors of the comorbidity patterns of chronic diseases. Results Potential category analysis identified 17 chronic diseases into five categories,of which 1 335 cases （27.24%） were cardiovascular metabolic disease comorbidities,1 719 cases （35.09%） were non-specific comorbidities,866 cases （17.69%） were gastric/rheumatoid arthritis comorbidities,497 cases （10.17%） were relatively healthy,and 481 cases （9.81%） were respiratory disease comorbidities. The results of disordered multivariate logistic regression analysis showed that higher age （OR=2.590）,higher BMI （OR=1.579）,smoking history （OR=4.655）,drinking history （OR=3.108）,family history of chronic diseases （OR=2.815）,and taking four or more medications daily （OR=4.581） were independent influencing factors for cardiovascular metabolic disease comorbidities （P<0.05）,while sleep time>6 hours （OR=0.562） and more exercise （OR=0.443） were protective factors （P<0.05）. Drinking history （OR=3.497） and family history of chronic diseases （OR=3.765） were independent influencing factors for non-specific comorbidities （P<0.05）. Higher age （OR=4.599）,drinking history （OR=6.619）,and taking four or more medications daily （OR=6.475） were independent influencing factors for gastric/rheumatoid arthritis comorbidities （P<0.05）. Higher age （OR=2.685）,smoking history （OR=2.832）,and family history of chronic diseases （OR=2.787） were independent influencing factors for respiratory disease comorbidities （P<0.05）. Conclusions In the Lujiang region,chronic disease patients generally have comorbidities,with cardiovascular and metabolic diseases being the most prevalent. Factors such as age,BMI,smoking history,family history of chronic diseases,sleep time,types of medication,and exercise frequency are associated with chronic disease comorbidities. It is recommended that relevant departments enhance the prevention and control of chronic diseases in these specific groups.

Key words: Chronic disease comorbidity, Prevalence rate, Investigation of current situation, Influencing factor