上海市成年健康体检人群非酒精性脂肪肝检出现状及危险因素分析

doi:10.12183/j.scjpm.2023.0397

摘要/Abstract

摘要： 目的探析上海市成年健康体检人群非酒精性脂肪肝（NAFLD）的检出现状及相关危险因素。方法选取2020年1—12月在华东疗养院行健康体检的成年人为研究对象,收集其基本资料和体检结果。采用Logistic回归模型分析NAFLD发生的可能相关危险因素。结果共纳入14 346名健康体检者,男7 623人,女6 723人,年龄18~90岁,平均（46.04±11.97）岁。共检出NAFLD 5 567例,总检出率为38.8%。多因素Logistic回归分析结果显示,女性NAFLD检出风险较男性低（OR=0.623）,年龄每增加1岁（OR=1.036）、中心性肥胖（OR=1.403）、饮食以荤食为主或高糖高盐饮食（OR=1.713）、血脂异常（OR=3.433）、空腹血糖增高（OR=3.664）、肝功能异常（OR=4.403）、高血压（OR=1.936）、尿酸增高（OR=2.712）的健康体检者NAFLD检出风险较高。结论上海市成年健康体检人群NAFLD检出较高,男性、年龄增加、中心性肥胖、荤食为主或高糖高盐饮食、肝功能异常、空腹血糖增高、血脂异常、尿酸增高、高血压是NAFLD发生的危险因素。

关键词: 非酒精性脂肪肝, 肥胖, 代谢异常, 健康体检者, 危险因素

Abstract: Objective To investigate the detection status of non-alcoholic fatty liver disease （NAFLD） and related risk factors in the adult health examination population in Shanghai. Methods Adults who underwent physical examination in Huadong Sanatorium from January to December 2020 were selected as the research objects, and their basic data and physical examination results were collected. The Logistic regression model was used to analyze the possible risk factors of NAFLD. Results A total of 14 346 healthy people were included, including 7 623 males and 6 723 females, aged 18-90 years, with an average of （46.04 ± 11.97） years. A total of 5 567 cases of NAFLD were detected, with a detection rate of 38.8%. Multivariate Logistic regression analysis showed that females were at less risk of NAFLD than males （OR=0.623）. The risk of NAFLD was higher in those with each increase of 1 year in age （OR=1.036）, central obesity （OR=1.403）, a meat-based diet or a diet high in sugar and salt （OR=1.713）, dyslipidemia （OR=3.433）, high fasting glucose （OR=3.664）, abnormal liver function （OR=4.403）, hypertension （OR=1.936）, and high uric acid （OR=2.712）. Conclusion The detection rate of NAFLD in adult health examination population in Shanghai is high. Male, age increase, central obesity, a meat-based diet or a diet high in sugar and salt, abnormal liver function, high fasting glucose, dyslipidemia, high uric acid, and hypertension are the risk factors for NAFLD.

Key words: Non-alcoholic fatty liver disease, Obesity, Metabolic abnormality, Health examination population, Risk factor

中图分类号:

R195

朱绘绘, 薛建华. 上海市成年健康体检人群非酒精性脂肪肝检出现状及危险因素分析[J]. 华南预防医学, 2023, 49(4): 397-401.

ZHU Huihui, XUE Jianhua. Detection rate and risk factors of non-alcoholic fatty liver disease in adult health examination population in Shanghai[J]. South China Journal of Preventive Medicine, 2023, 49(4): 397-401.

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