华南预防医学 ›› 2023, Vol. 49 ›› Issue (9): 1119-1123.doi: 10.12183/j.scjpm.2023.1119

• 论著 • 上一篇    下一篇

急性冠状动脉综合征患者出院一年内主要不良心血管事件发生情况及危险因素研究

李楠楠, 黄丽敏, 张小华   

  1. 东营市东营区人民医院,山东 东营 257000
  • 收稿日期:2023-04-28 出版日期:2023-09-20 发布日期:2023-11-07
  • 通讯作者: 张小华,E‐mail:dahai_2189@163.com
  • 作者简介:李楠楠(1982—),男,硕士研究生,主治医师,研究方向:冠心病

Incidence and risk factors of major adverse cardiovascular events in patients with acute coronary syndrome within 1 year after discharge

LI Nannan, HUANG Limin, ZHANG Xiaohua   

  1. Dongying District People's Hospital, Dongying 257000, China
  • Received:2023-04-28 Online:2023-09-20 Published:2023-11-07

摘要: 目的 分析急性冠状动脉综合征患者出院1年内主要不良心血管事件发生情况及其危险因素。方法 以2021年1—12月医院急性冠状动脉综合征存活出院患者为研究对象,收集患者的基本资料及相关临床资料,并进行出院后12个月的跟踪随访调查,描述性分析急性冠状动脉综合征存活出院患者主要不良心血管事件发生情况,并通过单、多因素分析方法分析主要不良心血管事件发生的危险因素。结果 完成基本资料及相关临床资料收集并成功跟踪随访共403例患者,发生不良心血管事件161例,发生率39.95%。主要不良心血管事件为再发住院(15.63%)、心律失常(9.93%)、心绞痛(5.96%)、心源性休克(3.23%)等。单因素发现不同年龄、高血压、糖尿病、冠状动脉严重病变程度、白细胞计数、血小板计数、应对方式、自我效能的急性冠状动脉综合征存活出院患者主要不良心血管事件发生率差异均有统计学意义(P<0.05或P<0.01)。多因素logistic回归分析提示年龄越大(OR=1.581)、高血压(OR=1.667)、糖尿病(OR=3.221)、冠状动脉严重病变程度高(OR=1.957)、白细胞计数升高(OR=1.522)、血小板计数升高(OR=1.539)、应对方式消极(OR=1.783)、自我效能低水平(OR=1.278)是急性冠状动脉综合征患者发生主要不良心血管事件的危险因素。结论 急性冠状动脉综合征患者出院1年内主要不良心血管事件发生风险较高,其受到多种危险因素影响,应关注高危群体,加强白细胞计数、血小板计数等监测,指导患者积极应对疾病,提高其自我效能,预防和减少不良心血管事件发生,改善预后。

关键词: 急性冠状动脉综合征, 出院, 不良心血管事件, 危险因素

Abstract: Objective To analyze the incidence and risk factors of major adverse cardiovascular events in patients with acute coronary syndrome within 1 year after discharge. Methods The patients with acute coronary syndrome who survived and were discharged from the hospital from January to December 2021 were taken for this study. The basic data and related clinical data of the patients were collected, and the follow‐up survey was conducted 12 months after discharge. The incidence of major adverse cardiovascular events in discharged patients with acute coronary syndrome was analyzed descriptively, and the risk factors of major adverse cardiovascular events were analyzed by univariate and multivariate analysis methods. Results A total of 403 patients completed the basic data and related clinical data collection and follow‐up, and 161 cases with adverse cardiovascular events, with an incidence of 39.95%. The main cardiovascular events were recurrent hospitalization (15.63%), arrhythmia (9.93%), angina pectoris (5.96%), and cardiogenic shock (3.23%). Univariate analysis showed that there were significant differences in the incidence of major adverse cardiovascular events in patients with acute coronary syndrome with different age, hypertension, diabetes, severity of coronary artery disease, white blood cell count, platelet count, coping style, and self‐efficacy (P<0.05 or P<0.01). Multivariate logistic regression analysis showed that older age (OR=1.581), hypertension (OR=1.667), diabetes (OR=3.221), severe coronary artery disease (OR=1.957), elevated white blood cell count (OR=1.522), elevated platelet count (OR=1.539), negative coping style (OR=1.783), and low self‐efficacy (OR=1.278) were risk factors for major adverse cardiovascular events in patients with acute coronary syndrome. Conclusions The risk of major adverse cardiovascular events within 1 year after discharge in patients with acute coronary syndrome is high, which is affected by many risk factors. We should pay attention to high‐risk groups, strengthen the monitoring of white blood cell count and platelet count, guide patients to actively respond to diseases, improve their self‐efficacy, prevent and reduce adverse cardiovascular events, and improve prognosis.

Key words: Acute coronary syndrome, Discharge, Adverse cardiovascular event, Risk factor

中图分类号: 

  • R195