孕妇疫苗临床试验研究进展

doi:10.12183/j.scjpm.2025.0371

摘要/Abstract

摘要： 孕期接种疫苗对保护母婴免受疾病侵害至关重要。然而,鉴于孕妇人群的特殊性,该人群往往被排除在临床试验之外,从而导致针对孕妇的疫苗使用缺乏足够的科学依据。开展孕妇疫苗临床试验可填补此类特殊人群疫苗接种相关数据,进而为制定科学合理的孕妇免疫接种指南提供依据。本文从孕妇接种疫苗的重要性、孕妇作为疫苗临床试验受试者的可行性,并以流感疫苗和含百日咳成分疫苗为例对孕妇疫苗试验的设计和要求等方面进行了综述。

关键词: 孕妇, 疫苗, 临床试验, 试验设计

中图分类号:

R186.3

黄芳, 朱晶晶, 黄卓英, 仇静, 李智, 李娟, 廖雨婷, 郭翔, 孙晓冬. 孕妇疫苗临床试验研究进展[J]. 华南预防医学, 2025, 51(4): 371-377.

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