华南预防医学 ›› 2025, Vol. 51 ›› Issue (11): 1187-1191.doi: 10.12183/j.scjpm.2025.1187

• 论著 • 上一篇    下一篇

移动流行区间法在云浮市不同型别流感病毒流行的应用研究

陈秋玲1, 廖晓文1, 赵惠珍1, 彭力荇1, 黄海锋2   

  1. 1.云浮市疾病预防控制中心,广东 云浮 527300;
    2.云浮市120急救调度中心
  • 收稿日期:2024-12-30 出版日期:2025-11-20 发布日期:2025-12-02
  • 通讯作者: 黄海锋,E-mail:1450142186@qq.com
  • 作者简介:陈秋玲(1990—),女,大学本科,主管医师,研究方向为疾病控制
  • 基金资助:
    云浮市医药卫生科研立项(2023B048)

An application study of the moving epidemic method for the surveillance of different influenza virus subtype epidemics in Yunfu

CHEN Qiuling1, LIAO Xiaowen1, ZHAO Huizhen1, PENG Lilao1, HUANG Haifeng2   

  1. 1. Yunfu Center for Disease Control and Prevention, Yunfu, Guangdong 527300, China;
    2. Yunfu 120 Emergency Dispatch Center
  • Received:2024-12-30 Online:2025-11-20 Published:2025-12-02

摘要: 目的 探索移动流行区间法(Moving Epidemic Method,MEM)建立云浮市不同型别流感流行预警模型,为流感防控工作提供参考依据。方法 利用2014年第36周至2023年第35周云浮市3家国家级流感哨点医院每周流感病原学监测数据,分别建立A(H1N1)pdm09亚型、A(H3N2)亚型和B(Victoria)系的流感病毒核酸检测阳性率MEM模型,制定不同流感型别的流行阈值和强度阈值,根据模型结果评价2023/2024年流行季不同流感型别的流行情况。结果 MEM模型结果显示,A(H1N1)pdm09亚型、A(H3N2)亚型和B(Victoria)系3种流感病毒核酸检测阳性率流行开始阈值分别为5.87%、14.58%和6.67%,A(H3N2)亚型的各级流行强度阈值最高,B(Victoria)系次之,A(H1N1)pdm09亚型的各级强度阈值最低。模型评价2023/2024年流行季A(H1N1)pdm09亚型达到高流行水平,A(H3N2)亚型处于低流行水平,B(Victoria)系达到中等流行水平。结论 MEM模型可应用于云浮市不同型别流感病毒流行水平预警。

关键词: 流感, 移动流行区间法, 流行强度, 预警

Abstract: Objective To investigate the utility of the Moving Epidemic Method(MEM) in establishing an epidemic warning model for various influenza virus subtypes in Yunfu, thereby providing an evidence-based reference for influenza prevention and control strategies. Methods Weekly virological surveillance data for influenza were collected from three national influenza sentinel hospitals in Yunfu, spanning from week 36 of 2014 to week 35 of 2023. The MEM was employed to construct models based on the nucleic acid detection positivity rates for influenza A(H1N1)pdm09 subtype, A(H3N2) subtype, and B(Victoria) lineage, respectively. Epidemic and intensity thresholds were subsequently established for each virus subtype. The resulting models were then utilized to assess the epidemic activity of these influenza subtypes during the 2023/2024 influenza season. Results The MEM-derived epidemic thresholds for the nucleic acid detection positivity rates of influenza A(H1N1)pdm09, A(H3N2), and B(Victoria) were determined to be 5.87%, 14.58%, and 6.67%, respectively. The A(H3N2) subtype exhibited the highest intensity thresholds across all levels, followed by the B(Victoria) lineage, whereas the A(H1N1)pdm09 subtype demonstrated the lowest intensity thresholds. Assessment of the 2023/2024 influenza season using these models indicated that the A(H1N1)pdm09 subtype reached a high level of epidemic activity, the A(H3N2) subtype remained at a low level, and the B(Victoria) lineage achieved a moderate level of epidemic activity. Conclusion The MEM is a viable tool for the epidemic surveillance and early warning of different influenza virus subtypes in Yunfu

Key words: Influenza, Moving epidemic method, Epidemic intensity, Early warning

中图分类号: 

  • R183.3