[1] Vaupel JW.Biodemography of human ageing[J]. Nature, 2010, 464(7288): 536-542. [2] Vollset SE, Goren E, Yuan CW, et al.Fertility, mortality, migration, and population scenarios for 195 countries and territories from 2017 to 2100: A forecasting analysis for the Global Burden of Disease Study[J]. Lancet, 2020, 396(10258): 1285-1306. [3] Petsko GA.A seat at the table[J]. Genome Biol, 2008, 9(12): 113. [4] Harper S.Economic and social implications of aging societies[J]. Science, 2014, 346(6209): 587-591. [5] Tian YE, Cropley V, Maier AB, et al.Heterogeneous aging across multiple organ systems and prediction of chronic disease and mortality[J]. Nat Med, 2023, 29(5): 1221-1231. [6] López-Ortiz S, Lista S, Peñín-Grandes S, et al.Defining and assessing intrinsic capacity in older people: A systematic review and a proposed scoring system[J]. Ageing Res Rev, 2022, 79: 101640. [7] McCabe EL, Larson MG, Lunetta KL, et al. Association of an index of healthy aging with incident cardiovascular disease and mortality in a community-based sample of older adults[J]. J Gerontol A Biol Sci Med Sci, 2016, 71(12): 1695-1701. [8] Dieteren CM, Samson LD, Schipper M, et al.The healthy aging index analyzed over 15 years in the general population: The Doetinchem Cohort Study[J]. Prev Med, 2020, 139: 106193. [9] Sanders JL, Minster RL, Barmada MM, et al.Heritability of and mortality prediction with a longevity phenotype: The healthy aging index[J]. J Gerontol A Biol Sci Med Sci, 2014, 69(4): 479-485. [10] Tu R, He H, Wang S, et al.The association between healthy aging index and trajectories of disability: A population-based cohort study[J]. Aging Clin Exp Res, 2022, 34(8): 1893-1900. [11] Yang J, Luo S, Liu Y, et al. Cohort profile: South China Cohort[J]. Int J Epidemiol, 2024, 53(2): dyae030. [12] Ma Z, Lv J, Zhu M, et al.Lung cancer risk score for ever and never smokers in China[J]. Cancer Commun (Lond), 2023, 43(8): 877-895. [13] Millwood IY, Walters RG, Mei XW, et al.Conventional and genetic evidence on alcohol and vascular disease aetiology: A prospective study of 500 000 men and women in China[J]. Lancet, 2019, 393(10183): 1831-1842. [14] Ito K, Tomata Y, Obuchi S, et al.Time spent walking and disability-free survival in older Japanese: The Ohsaki Cohort 2006 Study[J]. Scand J Med Sci Sports, 2022, 32(7): 1153-1160. [15] Wohlrab M, Klenk J, Delgado-Ortiz L, et al.The value of walking: A systematic review on mobility and healthcare costs[J]. Eur Rev Aging Phys Act, 2022, 19(1): 31. [16] Farvid MS, Sidahmed E, Spence ND, et al.Consumption of red meat and processed meat and cancer incidence: A systematic review and meta-analysis of prospective studies[J]. Eur J Epidemiol, 2021, 36(9): 937-951. [17] Fan M, Sun D, Zhou T, et al.Sleep patterns, genetic susceptibility, and incident cardiovascular disease: A prospective study of 385 292 UK biobank participants[J]. Eur Heart J, 2020, 41(11): 1182-1189. [18] American Diabetes Association.Diagnosis and classification of diabetes: Standards of care in diabetes-2024[J]. Diabetes Care, 2024, 47(Suppl 1): S20-S42. [19] Li X, Wei C, Hu K, et al.Regional differences in the association of healthy aging with the incidence of falls: An analysis based on the China Health and Retirement Longitudinal Study from 2011 to 2020[J]. Front Public Health, 2024, 12: 1416214. [20] Hu B.Childhood adversity and healthy ageing: A study of the Chinese older population[J]. Eur J Ageing, 2021, 18(4): 523-535. [21] Yin Z, Gao X, Zhang X, et al.Prevalence and correlates of healthy aging among elderly aged 65 years and over-6 PLADs, China, 2019[J]. China CDC Wkly, 2021, 3(4): 69-73. [22] Nie P, Li Y, Zhang N, et al.The change and correlates of healthy ageing among Chinese older adults: Findings from the China health and retirement longitudinal study[J]. BMC Geriatr, 2021, 21(1): 78. [23] Han S, Mo G, Gao T, et al.Age, sex, residence, and region-specific differences in prevalence and patterns of multimorbidity among older Chinese: Evidence from Chinese Longitudinal Healthy Longevity Survey[J]. BMC Public Health, 2022, 22(1): 1116. [24] Schaum N, Lehallier B, Hahn O, et al.Ageing hallmarks exhibit organ-specific temporal signatures[J]. Nature, 2020, 583(7817): 596-602. [25] Oh HS, Rutledge J, Nachun D, et al.Organ aging signatures in the plasma proteome track health and disease[J]. Nature, 2023, 624(7990): 164-172. [26] Tampubolon G.Trajectories of the healthy ageing phenotype among middle-aged and older Britons, 2004-2013[J]. Maturitas, 2016, 88: 9-15. [27] Li G, Tampubolon G, Maharani A, et al.Sex differences in allostatic load trajectories among midlife and older adults: Evidence from the China health and retirement longitudinal study[J]. PLoS One, 2024, 19(12): e0315594. [28] Naqvi S, Godfrey AK, Hughes JF, et al. Conservation, acquisition,functional impact of sex-biased gene expression in mammals[J]. Science, 2019, 365(6450): eaaw7317. [29] Sun Q, Xia X, He F.Longitudinal association between body mass index (BMI), BMI trajectories and the risk of frailty among older adults: A systematic review and meta-analysis of prospective cohort studies[J]. Arch Gerontol Geriatr, 2024, 124: 105467. [30] Jiang M, Zou Y, Xin Q, et al.Dose-response relationship between body mass index and risks of all-cause mortality and disability among the elderly: A systematic review and meta-analysis[J]. Clin Nutr, 2019, 38(4): 1511-1523. [31] Paluch AE, Bajpai S, Bassett DR, et al.Daily steps and all-cause mortality: A meta-analysis of 15 international cohorts[J]. Lancet Public Health, 2022, 7(3): e219-e228. [32] Lin YH, Chen YC, Tseng YC, et al.Physical activity and successful aging among middle-aged and older adults: A systematic review and meta-analysis of cohort studies[J]. Aging (Albany NY), 2020, 12(9): 7704-7716. [33] Gkotzamanis V, Panagiotakos DB, Yannakoulia M, et al.Sleep quality and duration as determinants of healthy aging trajectories: The HELIAD study[J]. J Frailty Aging, 2023, 12(1): 16-23. [34] Sabia S, Dugravot A, Léger D, et al.Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II Cohort Study[J]. PLoS Med, 2022, 19(10): e1004109. [35] Pan M, Tu R, Gu J, et al.Associations of socioeconomic status and physical activity with obesity measures in rural Chinese adults[J]. Front Public Health, 2020, 8: 594874. [36] Marks-Vieveen JM, Uijtdewilligen L, Motazedi E, et al.Physical activity levels, correlates, and all-cause mortality risk in people living with different health conditions[J]. J Phys Act Health, 2024, 21(4): 394-404. [37] Baker DP, Smith WC, Muñoz IG, et al.The population education transition curve: education gradients across population exposure to new health risks[J]. Demography, 2017, 54(5): 1873-1895. [38] Liao J, Zhang Y, Wang X, et al.Effects of education on adult mortality: A global systematic review and meta-analysis[J]. Lancet Public Health, 2024, 9(3): e155-e165. |