关键词: 磨玻璃结节, 健康体检人群, 代谢性疾病, 患病率, 糖尿病

Abstract: Objective To understand the prevalence of ground glass nodules （GGN） in health examination population in Shanghai and explore its correlation with metabolic diseases. Methods A total of 10 403 health examinees were selected for the survey,and the prevalence of GGN and metabolic indicators in this population were analyzed. Univariate and multivariate analyses were used to examine the impact of metabolic diseases on GGN. Results The prevalence of GGN in health examination population of the region was approximately 35.90% （3 735/10 403）,with females accounting for 38.87% （1 703/4 381） and males accounting for 33.74% （2 032/6 022）,with a statistically significant difference （P<0.05）. There was a statistically significant difference in the prevalence of GGN among patients with different metabolic diseases （P<0.05 or P<0.01）. Hypertension （OR=1.168） was a risk factor for GGN in the population. In addition to hypertension,high levels of low-density lipoprotein cholesterol （LDL-C） （OR=1.287） was a risk factor for GGN in females. For males,diabetes （OR=1.234）,impaired glucose regulation （OR=1.342）,and low levels of high-density lipoprotein cholesterol （HDL-C） （OR=1.315） were risk factors for GGN,while fatty liver （OR=0.858） was found to be a protective factor. Conclusions The prevalence of GGN is relatively high in health examination population in Shanghai. The prevalence of GGN in females is affected by hypertension and high levels of LDL-C,while the prevalence of GGN in males is related to hypertension,diabetes,impaired glucose regulation,low levels of HDL-C,and fatty liver.

Key words: Ground glass nodules, Health examination population, Metabolic diseases, Prevalence, Diabetes