Abstract: ObjectiveTo construct a comprehensive evaluation index system of food safety status and to provide a basic scientific method for rapid assessment of food safety in Guangdong Province.MethodsDelphi method was used with two rounds of expert consultation to screen and establish comprehensive indexes for evaluating food safety status. Weight coefficient of the indexes was computed by Fussy comprehensive evaluation method.ResultsNineteen experts conducted the first round of expert consultation survey. They were engaged in food safety related work for (19.1±7.0) years, 12 of them (63.2%) with senior or associate-senior professional titles. There were 18 experts in the second round, who were engaged in food safety related work for (18.9±7.8) years and 13 of whom (72.2%) had senior or associate-senior professional titles. The recovery rates were 73.1% for the first round and 94.7% for the second one.The expert judgment based on the average score was 0.925, the familiarity was 0.805, and the degree of the expert authority was 0.865.After two rounds of expert consultations, index system of food safety evaluation in Guangdong Province was established, including 5 first-level indicators and 17 second-level ones. The five first-level indicators were the Government investment in management,Food safety status,Relevant enterprise quality,Publicity andeducation, and Public satisfaction. The weight coefficients were between 0.190 and 0.209 for the five first-level indicators and between 0.024 and 0.200 for the 17 second-level ones.ConclusionThe food safety indicator system established in the study was well performed in the coordination degree of the expert opinion, the expert authority, and expert enthusiasm, and could be applied for the comprehensive evaluation of food safety in Guangdong Province.