Abstract: Objective To investigate the status of metabolic syndrome （MS） in postmenopausal women in Chengdu and its relationship with serum thyroid stimulating hormone （TSH）. Methods A stratified cluster sampling method was used to investigate postmenopausal women in Chengdu. The study content included questionnaire survey, physical examination and detection of blood biochemical indicators. Data were described and analyzed, and the correlation between MS and TSH was studied. Results A total of 3 512 postmenopausal women aged 40-74 years were surveyed in 2018 in Chengdu. Of the participants, 37.10% had the education level at primary school, 38.87% had the per capita monthly household income ranging from 3 000 to 4 999 Yuan, 76.74% had local household registration, 58.68% had the occupation of civilian post, 57.94% had family history of MS. MS was detected in 983 cases, with an incidence rate of 27.99%. TSH was positively correlated with BMI, waist-to-height ratio, fasting blood glucose, insulin resistance index, low-density lipoprotein cholesterol （LDL-C）, and triglyceride （r=0.860, 0.820, 0.819, 0.680, 0.718, 0.588）, and negative with high-density lipoprotein cholesterol （r =-0.668）. Multivariate logistic regression analysis showed that the higher the values of TSH （OR=1.952）, LDL-C （OR=1.861）, and HOMA-IR （OR=1.850）, the higher the risk of MS in menopausal women. Conclusion The incidence of MS was higher in postmenopausal women in Chengdu. The increase of TSH level was closely related to the incidence of MS.

Key words: Menopause, Serum thyrotropin, Metabolic syndrome