Abstract: Objective To understand the current situation of prevention and treatment of drinking water-type endemic fluorosis in Xinjiang Production and Construction Corps （hereinafter referred to as the Corps）, and to assess the non-carcinogenic health risk of fluoride in drinking water. Methods In 2019, all drinking water fluorosis areas in the Corps were monitored, including 11 divisions and 62 regiments. The monitoring contents included the operation of the water improvement project, the fluoride content in the water, and the prevalence of dental fluorosis among children aged 8 to 12 years. The risk assessment model of the United States Environmental Protection Agency （US EPA） was used to assess the health risk of fluoride intake through drinking water. Results In the regimental towns of drinking water-type fluorosis area, the water improvement rate was 100.00% （62/62）, the water improvement project was 100.00% in normal operation, the water fluoride content was 0.09 - 1.94 mg/L, and the qualified rate was 96.77% （60/62）; The water improvement rate of the farming and animal husbandry company was 100.00% （611/611）, the water fluoride content was 0.01-7.27 mg/L, and the qualified rate was 90.02% （550/611）; The total qualified rate was 90.64% （610/673）. The prevalence rate of dental fluorosis in children was 3.65% （1 564/42 839）, the dental fluorosis index was 0.07, and there was no epidemic of dental fluorosis. There was a statistically significant difference among divisions （P<0.01）. The prevalence rate of dental fluorosis in the 14th division was the highest （11.48%）; The non-carcinogenic health risk hazard coefficients of fluoride in both males and females aged 6 to 9 years were the highest, which were 0.29 and 0.30 respectively. Conclusions The water improvement rate of the drinking water-type fluorosis area of the Corps is high, the condition of children's dental fluorosis has been controlled. However, the water fluoride in some regimental towns and agricultural and animal husbandry companies still exceeds the standard, so it is necessary to strengthen the supervision of water improvement projects and the monitoring of water fluoride content.

Key words: Corps, Drinking water-type fluorosis, Dental fluorosis, Fluoride, Health risk assessment