Abstract: Objective To explore the effects of overweight/obesity and dyslipidemia and their interaction on blood pressure control in community hypertensive patients. Methods A total of 11 254 hypertensive patients with follow-up management in the medical community of Linping District Integrated Traditional Chinese and Western Medicine Hospital were selected for the study. The blood pressure control situation was analyzed by using the data of their health examination in 2021,and the influence of overweight/obesity and dyslipidemia on blood pressure control was analyzed by logistic regression model. The interaction between overweight/obesity and dyslipidemia on blood pressure control was analyzed using a multiplicative and additive model. Results The blood pressure control rate of hypertensive patients was 39.63%,and the proportion of patients with overweight/obesity and dyslipidemia were 60.41% and 58.00% respectively. Multivariate unconditional logistic regression analysis showed that overweight/obesity （OR=0.694） and dyslipidemia （OR=0.900） were both influential factors for blood pressure control （both P<0.01）. Interaction analysis showed that the blood pressure control of overweight/obesity with dyslipidemia was only 0.664 times that of non-overweight/obesity with normal blood lipids （95% CI：0.596-0.738）. The excess relative risk,interaction attribution ratio,and interaction index of overweight/obesity and dyslipidemia were -0.228 （95% CI：-0.289- -0.167）,-0.500 （95% CI：-0.626- -0.374）,and 1.721 （95% CI：1.244-2.381）,respectively. Overweight/obesity and dyslipidemia had additive interaction on blood pressure control. The multiplicative interaction between overweight/obesity and dyslipidemia on blood pressure control was not statistically significant （OR=0.987,95% CI：0.950-1.024）. Conclusion Overweight/obesity and dyslipidemia are important risk factors for blood pressure control in community hypertensive patients,and their additive interaction increases the risk of uncontrolled blood pressure in community hypertensive patients.

Key words: Hypertension, Overweight/obesity, Dyslipidemia, Interaction