Abstract: Objective To investigate the delayed recovery and its risk factors in patients with general anesthesia. Methods Patients who underwent general anesthesia in the Second Affiliated Hospital of Army Military Medical University,Ninth People's Hospital of Chongqing,and Chongqing West Hospital from June 2018 to June 2023 were selected by random number table method. The incidence of delayed recovery after general anesthesia was analyzed by descriptive analysis method,and its risk factors were analyzed by logistic regression. Results A total of 1 056 patients under general anesthesia were included in this study. The duration of stay in the post anesthesia care unit （PACU） after surgery was 30-98 minutes. Among them,196 cases （18.56%） had delayed recovery. Logistic regression analysis revealed that delayed recovery after general anesthesia was more likely to occur in patients aged 36-65 years （OR=4.541） and 66-78years （OR=6.413）,with cardiac function grade of Ⅱ （OR=3.685） and Ⅲ （OR=5.493）,higher BMI values （OR=3.466）,hypothermia （OR=3.173）,intraoperative additional anesthetic medication （OR=3.840）,increased intraoperative fluid volume administered （OR=3.419）,complicated with underlying diseases （OR=3.120）,longer anesthesia duration （OR=2.628）,emergency surgeries （OR=3.104）,central nervous system injuries （OR=3.426 ）,metabolic diseases （OR=3.769）,respiratory dysfunction （OR =3.276）,drinking habits （OR=2.878）,abnormal kidney function （OR=3.256）,abnormal blood perfusion of tissues and organs （OR=3.432）,and absolute or relative overdose of anesthetic drugs （OR=3.180）. Conclusions There is a high incidence of delayed recovery in patients with general anesthesia. Age,high BMI,hypothermia,excessive intraoperative fluid volume administered,intraoperative additional anesthetic medication,duration of anesthesia,emergency surgery,central nervous system injury,metabolic diseases,complicated with underlying diseases,cardiac function grade,respiratory dysfunction,drinking habits,abnormal kidney function,abnormal blood perfusion of tissues and organs,and absolute or relative overdose of anesthetic drugs are risk factors for delayed recovery after general anesthesia.

Key words: General anesthesia, Surgery, Delayed recovery, Influencing factor