Abstract: Objective To investigate the clinical and epidemiological characteristics of COVID-19 confirmed cases in Yunnan Province. Methods A retrospective study was used to analyze the general epidemiological data and clinical examination data of COVID-19 confirmed cases publicly released in Yunnan Province. Results There were 174 confirmed cases, aged 3-85 years old, with an average age of （41.7±18.1） years; 89 males （51.1%） and 85 females （48.9%）. All 14 prefectures and cities in the province had confirmed cases. After admission, the condition assessed was 21.3% for mild type, 68.8% for common type, 9.2% for severe type, and 0.7% for critically type; 98.9% were discharged from hospital and 1.1% died. Among the confirmed cases, 47.4% were from Hubei and 42.9% from Yunnan. 51.1% were from Wuhan to Yunnan, 11.5% had been to Wuhan, 11.5% had close contact with COVID-19 patients, and 24.7% had an unclear epidemiological history. In the first episode and clinical symptoms, fever, cough, sputum, and fatigue were the main manifestations. In laboratory tests, 95.5% of patients had normal or decreased white blood cells, 41.3% had a decrease in the count of lymphocyte, and 29.2% had a decrease in the percentage of lymphocytes; A small number of patients had elevated aspartate aminotransferase （AST） and alanine aminotransferase （ALT）. There was statistically significant difference in the proportion of fever in the first symptoms of mild/common type and severe/critical type （48.2% vs 78.6%, P < 0.05）. Conclusion Most patients with COVID-19 in Yunnan Province have a clear epidemiological history, and the population is generally susceptible, and there is no difference between genders. Most of the patients with clinical classification are common type, mainly manifested in fever, cough, sputum, fatigue, and good prognosis.

Key words: COVID-19, Yunnan Province, Clinical manifestation, Epidemiological characteristic