Abstract: Objective To investigate the mental health status of medical staff in COVID-19 designated hospital in a district of Beijing in 2020, so as to provide scientific basis for promoting the physical and mental health of medical staff during the fight against the epidemic. Methods Medical staffs in the front line of the designated hospital were selected as the study objects by cluster sampling method. On the 14th and 21st days after treatment, Symptom Checklist-90 （SCL-90） was used to investigate the mental health status of the medical staffs. Results A total of 66 medical staffs were included, including 24 males and 42 females, 22 doctors and 44 nurses, with an average age of （34.8±8.8） years. The positive detection rate of total score of SCL-90 for medical staff in the first investigation was 6.1% （4/66）, and in the second investigation was 7.6% （5/66）. In the second investigation, the positive detection rate of>30 years old group was lower than that in the ≤30 years old group （P<0.05）. The total mean scores of SCL-90 in both investigations were better than the Chinese norm （P<0.01）, and the score of the second investigation was lower than that of the first investigation, but the difference was not statistically significant （P>0.05）. And there was no statistically significant difference in the total mean scores of SCL-90 of medical staff with different genders, ages and occupations （P>0.05）. The factor scores of medical staff were lower than the Chinese norm. There was no statistical significance in the 10 factors of medical staff with different age and occupations （all P>0.05）, but there was statistical significance in the terror factors of medical staff with different genders （P<0.05）. The psychological quality of female was better. Conclusion In the prevention and control of COVID-19 epidemic, front-line medical staff can maintain a good mental health state, which is better than the normal adult norm in China. With the extension of working time on the front line, the mental health status of medical staffs aged over 30 years are better than that of younger comrades.

Key words: Symptom checklist, Medical staff, Mental health, COVID-19