Abstract: Objective To analyze the prevalence and influencing factors of pulmonary nodules among community residents with high risk of lung cancer in Maanshan City, and to provide a scientific basis for the prevention and treatment of lung cancer in Maanshan City. Methods From June to November 2020, the community residents who participated in the high risk assessment of lung cancer in Maanshan City and underwent low-dose spiral computed tomography （LDCT） of lung were selected as the subjects. The prevalence of pulmonary nodules was statistically described by a univariate analysis, and the influencing factors of pulmonary nodules were screened by a multivariate logistic regression analysis. Results In this study, 2 289 subjects were included, including 1 581 males （69.07%）, and 839 cases of pulmonary nodules were detected, with a detection rate of 36.65%. There were 293 cases of positive nodules （12.80%）, including 24 cases of suspected lung cancer （1.05%）. The detection rate of positive nodules was higher in males （38.02%） than in females （28.14%） （P<0.05）. The detection rate of positive nodules increased with age （P<0.05）. The detection rate of positive nodules was higher in those with incense burning habits （46.81%） than in those without incense burning habits （33.42%） （P<0.01）. Multivariate logistic regression analysis showed that pulmonary nodules were more likely to be detected in those with incense burning habits （OR=1.361）, outdoor physical activity （OR=1.238）, and organic solvent exposure （OR=2.107）. Conclusions The detection rate of pulmonary nodules in high-risk groups of lung cancer is higher in Maanshan City, and the prevalence of pulmonary nodules varies across ages and genders. Incense burning habits, exposure to organic solvents, participation in outdoor physical activity, and other factors are strongly associated with pulmonary nodules and risk factors should be addressed with necessary interventions.

Key words: Pulmonary nodules, Low-dose spiral computed tomography, Prevalence, Influencing factor