Abstract: Objective To investigate the status of asthenopia in occupational population in ophthalmology clinic and further analyze its influencing factors,to provide a reference for the prevention and treatment of asthenopia in occupational population. Methods Convenience sampling method was used to select the occupational population in Beijing who underwent physical examination in the ophthalmology clinic of a hospital in Beijing from July 2021 to June 2023 and had complete physical examination data. The basic personal conditions of the subjects were investigated,and the naked eye visual acuity,best corrected visual acuity,slit-lamp,and ophthalmoscopy were examined. Descriptive analysis was used to analyze the occurrence of asthenopia in occupational population,and univariate and multivariate analyses were used to analyze the related factors affecting asthenopia. Results In this study,2 104 occupational population were included,and 1 304 patients with asthenopia were detected,the detection rate was 61.98%,the naked eye visual acuity was 0.1-1.2,the best corrected visual acuity was > 1.0,and the slit-lamp examination did not detect the keratoconjunctival lesion. Multivariate Logistic regression analysis showed that age （OR=1.865）,education level （OR=1.702）,diabetes （OR=1.914）,occupation type （OR=2.277 for employees of enterprises and public institutions,OR=2.298 for civil servants）,higher intensity eye use （OR=1.788）,longer working years （OR=1.919）,and longer myopia （OR=2.208）were the risk factors for asthenopia in the occupational population,while sleep duration （OR=0.738）was a protective factor. Conclusion The detection rate of asthenopia in the professional population is high,so the visual monitoring and publicity of the professional population should be strengthened to alleviate asthenopia.

Key words: Asthenopia, Occupational population, Living habit, Influencing factor