Objective To explore the occurrence and related factors of pelvic floor dysfunction in women with natural childbirth and provide the scientific basis for reducing the occurrence of postpartum pelvic floor dysfunction. Methods From June 2021 to June 2023,pregnant women who delivered spontaneously and received postpartum follow-up and return visit 42 days after delivery in the Obstetrics Department of Huainan Maternal and Child Health Hospital,the First Affiliated Hospital of Anhui University of Science and Technology,and General Hospital of Huainan Oriental Hospital Group were selected for the study. Birth-related data were collected and pelvic floor muscle strength was detected. Descriptive analysis method was used to analyze the occurrence of pelvic floor dysfunction,and univariate and multivariate analysis methods were used to analyze the influencing factors of pelvic floor dysfunction. Results Out of 1 823 women with natural childbirth,782 cases were found to have pelvic floor dysfunction,with an incidence rate of 42.90%. The results of multivariate logistic regression showed that the risk of pelvic floor dysfunction was higher in women with natural childbirth who aged ≥35 （OR=2.869）,with history of pelvic surgery （OR=1.579）,absence of anal contraction training during pregnancy （OR=2.482）,presence of pregnancy complications （OR=3.043）,weight gain during pregnancy higher than recommended standards （OR=2.776）,presence of urinary incontinence during pregnancy （OR=2.298）,failure to follow medical advice for pelvic floor rehabilitation exercise （OR=2.474）,long duration of second stage of labor （OR=2.907）,high newborn body weight （OR=2.575）,and postpartum urinary tract infection （OR=1.929）. Conclusions The detection rate of pelvic floor dysfunction in women with natural childbirth is relatively high,and the high-risk women mainly include those aged ≥ 35,with history of pelvic surgery,absence of anal contraction training during pregnancy,presence of pregnancy complications,weight gain during pregnancy higher than recommended standards,presence of urinary incontinence during pregnancy,failure to follow medical advice for pelvic floor rehabilitation exercise,long duration of second stage of labor,high newborn body weight,and postpartum urinary tract infection. To reduce the risk of pelvic floor dysfunction,accordingly,targeted interventions or preventive measures can be given to at-risk pregnant women.

Objective To analyze the HPV vaccination intention of college students in Xinjiang and its influencing factors based on the information-motivation-behavior （IMB）model,and to provide a reference for the promotion of HPV vaccine among college students in Xinjiang. Methods The stratified cluster sampling was used to conduct a questionnaire survey on college students from three universities in Xinjiang to collect HPV vaccination intention,socio-demographic characteristics,attitudes towards vaccine and sexual behavior,HPV-related information,and motivation and behavioral skills to vaccinate HPV vaccine. The c² test and t-test were used to compare the differences between groups. Unconditional multifactorial logistic regression was used to explore the influencing factors of HPV vaccination intention among college students. Results Among the 834 college students in Xinjiang,559 （67.0%）had the intention to receive HPV vaccination. College students who were female （OR=3.219）,had actively searched for or consulted HPV vaccine （OR=2.630）,had mild perceptual impairment （OR=0.626）,and had higher social motivation （OR=1.959）had higher HPV vaccination intention （P<0.05）. Conclusions The overall HPV vaccination intention of college students in Xinjiang is high,and the vaccination intention of male students needed to be further improved. Focusing on improving college students' cognitive level of HPV and social motivation for HPV vaccination,reducing college students' perceived barriers to HPV vaccination,and adjusting male HPV prevention strategies will effectively improve the HPV vaccination intention of college students in Xinjiang.

Objective To understand the sleep status and influencing factors of children and adolescents in Shenzhen,and provide theoretical basis for promoting their sleep health. Methods In 2021,multi‐stage stratified cluster random sampling method was adopted to select elementary and secondary school students in Shenzhen for physical examination and questionnaire survey. Chi‐square test and logistic regression analysis method were used to analyze the sleep status and influencing factors of elementary and secondary school students in Shenzhen. Results The average sleep duration of 4 534 children and adolescents was （9.23±1.01） h,with 54.67% having insufficient sleep and 35.64% having sleep disorders. Grades 4-6 （OR=1.656）,high school （OR=0.797）,graduating class （OR=1.899）,mother's education level was high school/vocational school/technical school （OR=0.744）,and mother's education level was junior high school or below （OR=0.613） were influencing factors for insufficient sleep among children and adolescents. High school （OR=2.753） and screen time≥2 h/d （OR=1.290） were influencing factors for sleep disorders among children and adolescents. Conclusions There are many sleep problems among children and adolescents in Shenzhen. School period,mother's education level,and screen time are the main influencing factors. Parents and schools should give comprehensive intervention according to the influencing factors of sleep to improve the sleep status of children and adolescents.

Objective To understand the prevalence and influencing factors of dyslipidemia in adults in Shenzhen,and to provide reference for the prevention and control strategy of dyslipidemia in Shenzhen. Methods A multi‐stage stratified random sampling method was used to conduct questionnaire survey,physical examination,and laboratory testing among permanent residents aged ≥18 years in 10 districts of Shenzhen from April to December 2021. Multivariate logistic regression was used to analyze the influencing factors of dyslipidemia. Results A total of 6 285 adults were included,with a mean age of （40.27±14.24） years old,and male to female ratio was 0.99∶1,2 300 of the participants were dyslipidemia,the prevalence rate was 36.60% （the standardized prevalence rate was 38.35%）. The results of multivariate analysis showed that females （OR=0.758） and underweight （OR=0.446） were protective factors for dyslipidemia of adults in Shenzhen,and 35-64 years old （OR=1.832）,65-94 years old （OR=1.811）,overweight （OR=1.719）,obesity （OR=2.289）,current smoking （OR=1.409）,hypertension （OR=1.575）,diabetes （OR=2.285）,hyperuricemia （OR=1.953） were the risk factors. Conclusions The prevalence of dyslipidemia in adults in Shenzhen is high,and it is necessary to strengthen the monitoring of blood lipids and intervention of lifestyle in high‐risk groups such as older men,overweight and obese,smoking and chronic diseases,so as to prevent the occurrence of dyslipidemia.

Objective To explore and analyze the results of hearing screening combined with deafness gene screening among neonates in Nanjing. Methods Neonates delivered at the Department of Obstetrics and Gynecology of Nanjing Jiangning Hospital,Nanjing Drum Tower Hospital,and Nanjing Hospital of Chinese Medicine from January 2020 to December 2022 were selected to conduct hearing screening combined with deafness gene screening. Otoacoustic emission and automatic auditory brainstem response were used for hearing screening. Deafness gene screening was performed to detect GJB2 gene,GJB3 gene,SLC26A4 gene,and mitochondrial 12SrRNA. Results A total of 13 256 neonates were included in this study,including 6 870 males and 6 386 females. There were 658 neonates identified with deafness gene mutation,resulting in a detection rate of 4.96%. Among them,there were 656 cases exhibiting single locus mutation across four genes,with a detection rate of 4.90%. Specifically,there were 382 neonates presenting GJB2 gene mutation with a mutation rate of 2.88%,while the occurrence of GJB3 and SLC264A gene mutations was observed in 34 neonates （mutation rate：0.26%）and 212 neonates （mutation rate：1.60%）,respectively. Additionally,mitochondrial DNA mutation was found in 22 neonates at a frequency of 0.17%. Furthermore,double/double-gene heterozygous mutations accounted for only 10 cases （mutation rate：0.08%）,including 6 cases of GJB2-235/GJB2-299 double heterozygous mutations （mutation rate：0.05%）and 4 cases of GJB3/SLC26A4 double-gene heterozygous mutations （mutation rate：0.03%）. Among 658 neonates with deafness gene mutation,12 cases were diagnosed with hearing loss,and the detection rate was 1.82%. Among 12 598 neonates without deafness gene mutation,12 cases were diagnosed with hearing loss after hearing screening and re-screening,and the detection rate was 0.10%. The detection rate of hearing loss in neonates with deafness gene mutation was significantly higher than that in neonates without deafness gene mutation （P<0.01）. The detection rate of hearing loss was significantly higher in neonates with preterm birth and external ear deformity （both P < 0.01）. Conclusions GJB2 gene and SLC264A gene are the main mutation types of deafness gene in neonates in Nanjing. Hearing screening combined with deafness gene screening can significantly improve the detection rate of hereditary deafness in neonates,which is conducive to early prevention and treatment.

Objective To explore the current situation of readmission in patients with chronic heart failure and analyze its influencing factors,so as to provide the reference for reducing the risk of readmission. Methods Patients with chronic heart failure hospitalized in a hospital in Qingdao City from January 2019 to December 2021 were selected for this survey. Demographic data,cardiac function grading data,and related physiological and biochemical test results before discharge were collected,and readmission follow-up within 1 year of discharge was carried out. Descriptive analysis method was used to describe readmission status,univariate and multivariate analysis methods were used to analyze the relevant factors of readmission. Results A total of 2 229 patients with chronic heart failure were included as the study subjects. During a one-year follow-up period after discharge,9 died and 4 were lost to follow-up. Finally,2 216 patients were included,of whom 59.61% were males and 40.39% were females,aged 49-91,with a course of disease of 0.1-13 years,and mainly 5-10 years （35.29%）. During the one-year follow-up period,973 cases were readmitted,with a readmission rate of 43.91%. Among them,372 cases （16.79%） were readmitted within 3 months after discharge,and 889 cases （40.12%） were readmitted within 6 months. The Cox regression model analysis showed that age （HR=1.895）,living alone （HR=1.793）,course of disease （HR=3.053）,cardiac function grading at discharge （HR=11.462）,LVEF≤35% （HR=3.518）,complicated with renal insufficiency （HR=6.801）,malnutrition （HR=5.058）,elevated brain natriuretic peptide （HR=6.190）,anemia （HR=6.373）,depression （HR=3.435）,medication adherence （HR=0.107）,low sodium and water limited diet （HR=0.159）,and regular aerobic exercise （HR=0.209） were independent influencing factors that affect readmission of patients with chronic heart failure within one year of follow-up after discharge. Conclusions Patients with chronic heart failure have a high risk of short-term readmission,which is mainly concentrated in 3-6 months after discharge. Attention should be paid to high-risk groups such as the elderly,living alone,with a long course of disease,and complicated with renal insufficiency and anemia. Patients should be encouraged to adhere to a low-salt diet and regular aerobic exercise lifestyle after discharge,and cultivate good medication adherence and maintain a good attitude. Thus,the risk of readmission can be effectively reduced and the quality of life can be improved.