Abstract: ObjectiveTo analyze changes of the incidence trend of malignant tumor in Chongqing Municipality from 2006 to 2015 and the influencing factors, so as to provide the evidence for prevention and control of malignant tumor.MethodsCancer cases newly reported from 2006 to 2015 were collected from the cancer registries in Chongqing. The data were analyzed to calculate the incidence, Chinese age-standardized incidence rate, and percentage of annual changes of malignant tumor. The incidence trend of malignant tumor was identified by curve estimated exponential distribution regression model. The contribution rate of demographic and non-demographic factors to different incidence trend of malignant tumor was analyzed by the difference decomposing of incidence.ResultsThe incidence rate and Chinese age-standardized rates of malignant tumor increased from 148.08/105 and 131.44/105 in 2006 to 269.39/105 and 177.13/105 in 2015, and the APC was 5.65% and 2.43%, respectively (P<0.05 or P<0.01). The incidence of malignant tumor was higher in males than that in females. The contribution rates due to demographic and non-demographic factors for the increased incidence of malignant tumor were 66.32% and 33.68%, respectively. The contribution rates of demographic factor were higher in male, female, and rural area (80.76%, 51.06%, 114.68%) than those of non-demographic factor (19.24%, 48.94%, -14.68%). But in urban area, the contribution rate of non-demographic factor (64.29%) was higher than that of demographic factor (35.71%).ConclusionThe incidence of malignant tumor presented a rising trend in Chongqing, and the rising trend was synergistically affected by the demographic and non-demographic factors.