慢性胃炎患者幽门螺杆菌检出现状及影响因素研究

doi:10.12183/j.scjpm.2023.0156

摘要/Abstract

摘要： 目的研究慢性胃炎患者幽门螺杆菌检出情况及影响因素,为预防幽门螺杆菌相关慢性胃炎提供借鉴资料。方法以2021年1—12月屯昌县人民医院及海南医学院第一附属医院诊治的慢性胃炎患者为研究对象,采用¹³C-尿素呼吸试验检测幽门螺杆菌,并收集患者的人口学信息及消化系统疾病相关行为情况,采用描述性分析方法对慢性胃炎患者幽门螺杆菌检出情况进行分析,并采用单、多因素分析方法对慢性胃炎患者幽门螺杆菌感染影响因素进行分析。结果 1 126例慢性胃炎患者中男589例,女537例,年龄26~73岁,以50~59岁所占比例较高,为36.86%;居住地农村者491例,城镇635例。病程以6~12个月居多,占57.29%。幽门螺杆菌阳性421例,阳性检出率37.39%。多因素Logistic回归分析显示年龄（OR=2.115）、家庭成员感染史（OR=3.600）、病程（OR=1.507）、饮酒习惯（OR=1.988）、幽门螺杆菌认知水平（OR=0.614）是慢性胃炎患者幽门螺杆菌感染的影响因素。结论慢性胃炎患者幽门螺杆菌感染检出率较高,感染现状不容乐观,其受到多种因素影响,应针对各项因素加强防治,加强感染筛查,降低感染风险。

关键词: 幽门螺杆菌, 慢性胃炎, ¹³C-尿素呼吸试验, 影响因素

Abstract: Objective To study the detection and influencing factors of Helicobacter pylori in patients with chronic gastritis, and to provide the reference for prevention of Helicobacter pylori-related chronic gastritis. Methods Patients with chronic gastritis diagnosed and treated at the People's Hospital of Tunchang County and the First Affiliated Hospital of Hainan Medical College from January to December 2021 were selected. The ¹³C-urea breath test was used to detect Helicobacter pylori. Demographic information and behaviors related to digestive disorders of the patients were collected, and the detection of Helicobacter pylori in patients with chronic gastritis was analyzed by descriptive analysis. The influencing factors of Helicobacter pylori infection in patients with chronic gastritis were analyzed by univariate and multivariate analysis methods. Results Among the 1 126 patients with chronic gastritis, there were 589 males and 537 females, aged 26-73 years old, with the proportion of 50-59 years old accounting for 36.86%; there were 491 cases in rural areas and 635 cases in urban areas. The course of disease was higher in 6-12 months, accounting for 57.29%. A total of 421 cases tested positive for Helicobacter pylori, with a positive rate of 37.39%. Multivariate Logistic regression analysis showed that age （OR=2.115）, family history of infection （OR=3.600）, course of disease （OR=1.507）, drinking habit （OR=1.988）, and cognitive level of Helicobacter pylori （OR=0.614） were influencing factors of Helicobacter pylori infection in patients with chronic gastritis. Conclusions The detection rate of Helicobacter pylori infection in patients with chronic gastritis is high and the status of the infection is not optimistic, which is affected by various factors. Prevention and treatment should be strengthened according to various factors, and infection screening should be strengthened to reduce the risk of infection.

Key words: Helicobacter pylori, Chronic gastritis, ¹³C-urea breath test, Influencing factor

中图分类号:

R195

肖婵, 曾小平, 王时波, 郑达江, 吴海琴. 慢性胃炎患者幽门螺杆菌检出现状及影响因素研究[J]. 华南预防医学, 2023, 49(2): 156-159.

XIAO Chan, ZENG Xiao-ping, WANG Shi-bo, ZHENG Da-jiang, WU Hai-qin. Detection of Helicobacter pylori in patients with chronic gastritis and its influencing factors[J]. South China Journal of Preventive Medicine, 2023, 49(2): 156-159.

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