Abstract: Objective To understand the trend of disease burden of cerebral hemorrhage and cerebral infarction from 2012 to 2018 in Chongqing, and provide the suggestion for conducting the pertinent intervention. Methods The data of stroke cases in Chongqing from 2012 to 2018 were from the National System for Registering and Reporting Cardiovascular and Cerebrovascular Events of Chinese Center for Disease Control and Prevention. The incidence, standardized morbidity, mortality, standardized mortality, disability adjusted life years （DALY）, years of life lost （YLL） and years lived with disability （YLD） were calculated for stroke, cerebral hemorrhage and cerebral infarction. The change trend of rate was indicated by annual percentage change （APC）, and the t-test was carried out on APC. Results The rate of YLD of stroke, cerebral hemorrhage and cerebral infarction increased from 3.37‰, 0.91‰, 2.46‰ in 2012 to 4.03‰, 1.01‰, 2.64‰ in 2018 respectively. And its APC was 3.67%, 4.39% and 1.61% respectively. The change trend of YLD of stroke was statistically significant （P<0.01）. The rate of YLL of stroke, cerebral hemorrhage and cerebral infarction increased from 18.38‰, 11.61‰, 3.29‰ in 2012 to 20.10‰, 12.01‰, 5.40‰ in 2018 respectively. And its APC was 1.01%, 0.40% and 7.68% respectively. The change trend of YLL of cerebral infarction was statistically significant （P<0.01）. The rate of DALY of stroke, cerebral hemorrhage and cerebral infarction increased from 21.75‰, 12.52‰, 5.75‰ in 2012 to 24.13‰, 13.02‰, 8.04‰ in 2018 respectively. And its APC was 1.51%, 0.70% and 5.34% respectively. The change trend of DALY of cerebral infraction was statistically significant （P<0.01）. Conclusion The rate of DALY of stroke in Chongqing was lower than national average level. The proportion of cerebral hemorrhage was over 50% of all stroke. The disease burden of cerebral infraction increased year by year in Chongqing. It should be attached importance on stroke control and prevention to curb the rapid increasing of cerebral infarction and raise the capability for cerebral hemorrhage.

Key words: Stroke, Cerebral infarction, Cerebral hemorrhage, Disease burden