Abstract: Objective To analyze the prevalence, morbidity, mortality, and disability adjusted life years （DALYs） of thyroid carcinoma in Jiangsu Province from 1990 to 2019 and their trends. Methods The standardized prevalence, morbidity, mortality, and DALYs rate of thyroid carcinoma in Jiangsu Province from 1990 to 2019 were analyzed which were based on 2019 Global Burden of Disease Study（GBD 2019） database. Joinpoint software was used to analyze the trend of standardized rate and calculate the average annual percentage change （AAPC）. Results From 1990 to 2019 in Jiangsu Province, the standardized prevalence of thyroid carcinoma increased from 5.22/10⁵ to 14.68/10⁵, the standardized morbidity increased from 0.84/10⁵ to 1.80/10⁵, the standardized mortality decreased from 0.35/10⁵ to 0.28/10⁵, and the standardized DALYs rate decreased from 8.34/10⁵ to 6.91/10⁵. The standardized prevalence and morbidity showed an upward trend （AAPC=3.6%, P<0.05; AAPC=2.9%, P<0.05）, the rising trends were showed in both females and males, males were higher than females. The standardized mortality and DALYs rate showed a downward trend in whole population （AAPC=-0.9%, P<0.05; AAPC=-0.6%, P<0.05）, females were as same as the whole population, but males were opposite which were still increasing. Conclusions From 1990 to 2019 in Jiangsu Province, the standardized prevalence and morbidity of thyroid carcinoma were on the rise, while the standardized mortality and DALYs rate had been falling. The standardized prevalence, morbidity, mortality, and DALYs rate of male patients all demonstrated the rising trends, which should be paid more attention to.

Key words: Thyroid carcinoma, Disease burden, Prevalence, Morbidity, Mortality