Abstract: Objective To investigate the status and influencing factors of secondary prevention in patients with ischemic stroke. Methods ?Patients diagnosed with ischemic stroke between January and July 2022 at the First Affiliated Hospital of Xinxiang Medical College, all of whom had a doctor's order and prescription for secondary prevention drugs, were selected for a questionnaire survey on status of secondary prevention. Descriptive analysis method was used to analyze the status of secondary prevention in this population, and univariate and multivariate analysis methods were used to analyze the influencing factors of secondary prevention. Results A total of 1 283 patients with ischemic stroke were included in the study, including 716 males and 567 females, aged 43-79. The proportion of patients with a course of disease of 1-5 years was high, accounting for 67.97%. The compliance of secondary prevention was 23.77%. Multivariate Logistic regression analysis suggested that education level （OR=1.198）, living style （spouse/child living together OR=1.317）, other basic diseases （OR=1.960）, personal health literacy （OR=2.841）, and social support （OR=2.212） were influencing factors for secondary prevention compliance in patients with ischemic stroke. Conclusions The compliance of secondary prevention in patients with ischemic stroke needs to be improved. Depending on the influencing factors, attention should be paid to patients with low education, living alone, and complicated by other basic diseases. Targeted measures should be taken to improve their personal health literacy and social support, and promote improved secondary prevention compliance to facilitate the control of disease development and reduce recurrences.

Key words: Ischemic stroke, Secondary prevention, Compliance, Influencing factor