Abstract: Objective To explore the maternal and infant outcomes of pregnancy-induced hypertension syndrome （PIH） and its influencing factors, so as to provide scientific basis for avoiding adverse delivery outcomes in special populations. Methods The PIH gravida who established prenatal health records in a hospital in Beijing from June 2017 to May 2020 and gave birth in the hospital were used as the research object to collect the relevant physiological and biochemical indicators and delivery status of PIH patients when they were diagnosed with PIH. Descriptive epidemiological analysis was used to analyze the adverse delivery outcomes of PIH gravida, and univariate and multivariate analysis methods were used to analyze the related factors of the population's adverse delivery outcomes. Results A total of 274 effective cases of gravida diagnosed with PIH was collected during the study period, aged 23-43 years old, mainly 23-34 years old, accounting for 63.87%. Primiparas accounted for 60.95%, regular obstetric checkups accounted for 94.89%, and family history of hypertension accounted for 29.93%. The incidence of adverse maternal and infant outcomes was 31.39% （86/274）, including 27 cases of placental abruption, 23 cases of postpartum hemorrhage, 8 cases of postpartum infection, 6 cases of oligohydramnios, 12 cases of fetal distress, and 10 cases of neonatal asphyxia. The degree of disease was moderate or severe （OR=2.042, 2.305）, the degree of urine protein was +++ or ++++ （OR=2.550, 2.942）, combined with hypothyroidism （OR=2.686）, a history of smoking （OR= 2.968） and those with abnormal LDL-C, HDL-C, ApoA1, VEGF, sVEGFR-1 （OR=1.446, 1.726, 1.976, 2.430, 1.774） had a higher risk of adverse maternal and infant outcomes. Gestational age at onset≥ 37 weeks （OR=0.515）, and those with delivery gestational age ≥37 weeks （OR=0.506） had a lower risk of adverse maternal and infant outcomes. Conclusion PIH patients have a higher risk of adverse delivery outcomes, and there are many factors that may affect delivery outcomes. It is recommended that the relevant risk factors of this population should be monitored and related prevention and control measures should be formulated to avoid adverse maternal and infant outcomes.

Key words: Pregnancy-induced hypertension syndrome, Pregnancy complications, Maternal and infant outcome, Pregnancy outcome, Influencing factor