Abstract: Objective To investigate the status of emergency response ability of medical staff in tertiary medical institutions in Wuhan region for public health emergencies and analyze relevant influencing factors, to provide theoretical basis for further improving the emergency response ability of relevant personnel for public health emergencies. Methods By convenient sampling method, 2 976 medical staff from three tertiary medical institutions in Wuhan were selected to conduct a questionnaire survey on emergency response ability, emergency knowledge, and emergency attitude of public health emergencies. The demographic characteristics of medical staff were collected to analyze the influencing factors of emergency response ability. Results The average score of the emergency response ability of 2 976 medical staff for public health emergencies was （142.74±10.93） points, and the average score of the total items was （3.86±0.53） points. Among the scores of each dimension of emergency response ability, the item of protection ability had the highest average score, and the item of preparedness ability had the lowest average score. The emergency response ability of medical staff for public health emergencies was positively correlated with emergency knowledge and attitude （r=0.704, 0.513, both P<0.05）. Multiple linear regression analysis showed that major type （β'=0.821, 0.635, 0.524）, working years （β'=0.779）, participation in emergency training/drills （β'=2.278）, emergency knowledge （β'=1.349）, and emergency attitude （β'=1.125） were the main influencing factors affecting the emergency response ability of medical staff for public health emergencies. Conclusions The medical staff of tertiary medical institutions in this region lack emergency training/drills for public health emergencies and actual emergency work experience. It is necessary to strengthen emergency knowledge learning and improve cognitive level, so as to further improve the emergency response ability of medical staff.

Key words: Medical staff, Public health emergency, Emergency response ability, Investigation